Structure mirroring function: What's the ‘matter’ with the funny current?
Abstract figure legend The ‘funny’ (If) current of cardiac pacemaker cells has been first identified in the late 1970s as a major mechanism in the generation and control of cardiac pacemaking. Decades of studies have since described the properties of the funny current and of its molecular components, HCN channels, in the heart and brain, providing the ...
Andrea Saponaro, Dario DiFrancesco
wiley +1 more source
AIM: To evaluate the efficiency and safety of an interchange of atenolol and ivabradine in patients who had stable angina pectoris without myocardial infarction in the history and left ventricular (LV) systolic dysfunction/MATERIAL AND METHODS: The trial
A A Shavarov +2 more
doaj
Management of Stable Angina with Ivabradine as Safe Alternative to Patients with Myasthenia Gravis
Management of cardiac symptoms in myasthenia gravis (MG) patients can be challenging. The aim of this report is to describe the safe use of ivabradine for stable angina in MG patients. A 48 y.o.
Giuliano Ohde Dalledone +7 more
doaj +1 more source
Clinical trial updates and hotline sessions presented at the European Society of Cardiology Congress 2008 [PDF]
This article summarizes the results of a number of clinical trials in the field of cardiovascular medicine which were presented during the Hotline and Clinical Trial Update Sessions at the annual meeting of the European Society of Cardiology, held in ...
Adam, Oliver +4 more
core +2 more sources
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley +1 more source
The role of inhibitory G proteins and regulators of G protein signaling in the in vivo control of heart rate and predisposition to cardiac arrhythmias [PDF]
Inhibitory heterotrimeric G proteins and the control of heart rate. The activation of cell signaling pathways involving inhibitory heterotrimeric G proteins acts to slow the heart rate via modulation of ion channels.
Ang, R, Opel, A, Tinker, A
core +1 more source
The Thoracic Lymphatic Vasculature: Interorgan Strategies to Achieve an Optimal Tissue Function
In the thorax, organ‐specific features such as stomata and submesothelial lacunae, pulmonary perivascular and peribronchial vessels, and subepicardial lymphatic network allow the thoracic lymphatics to perform as a dynamically regulated system able to exploit local mechanical forces and tissue‐specific architecture to maintain fluid and solute ...
Daniela Negrini +3 more
wiley +1 more source
Cost‐Effectiveness of Ivabradine for Heart Failure in the United States
BackgroundIvabradine is a heart rate–lowering agent approved to reduce the risk of hospitalization for worsening heart failure. This study assessed the cost‐effectiveness of adding ivabradine to background therapy in the United States from the ...
Anuraag R. Kansal +6 more
doaj +1 more source
Has the 'epidemic’ of heart failure been replaced by a tsunami of co-morbidities? [PDF]
No abstract ...
Bhatt +17 more
core +1 more source
A Multi-marker Model for Predicting Decompensated Heart Failure in Patients with Prior Acute Myocardial Infarction [PDF]
The aim of the study was to assess the prognostic value of determining the plasma concentration of NT-proBNP and ST2 in the patients with decompensated HF and prior acute myocardial infarction and their combination in this category of patients.Materials ...
Levandovska, K. (Khrystyna)
core +3 more sources

