Results 111 to 120 of about 67,505 (283)

Development of an in vitro drug sensitivity assay for Trichuris muris first-stage larvae [PDF]

open access: yes, 2013
Trichuriasis represents a major public health problem in the developing world and is regarded as a neglected disease. Albendazole and mebendazole, the two drugs of choice against trichuriasis display only moderate cure rates, hence alternative drugs are ...
Keiser, Jennifer   +2 more
core   +2 more sources

Ivermectin, a new candidate therapeutic against SARS-CoV-2/COVID-19

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2020
© The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the ...
K. Sharun   +9 more
semanticscholar   +1 more source

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl   +6 more
wiley   +1 more source

An empirical method to estimate the effect of soil on the rate for transmission of damping‐off disease

open access: yes, 2004
The ability of some soils to suppress soil-borne diseases has been long recognised, but the underlying epidemiological mechanisms by which this occurs are largely unknown.• Using damping-off disease caused by Rhizoctonia solani, spreading through ...
Alabouvette C   +19 more
core   +1 more source

First documentation of in vivo and in vitro ivermectin resistance in Sarcoptes scabiei [PDF]

open access: yes, 2004
Ivermectin is increasingly being used to treat scabies, especially crusted (Norwegian) scabies. However, treatment failures, recrudescence, and reinfection can occur, even after multiple doses.
Currie, Bart John   +3 more
core   +1 more source

Reading Nietzsche in an Age of Conspiracy Theories

open access: yesModern Theology, EarlyView.
Abstract This essay considers Friedrich Nietzsche's critique of Christian morality as a template for interpreting the epistemology of modern conspiracy theorists. The first section elucidates Nietzsche's notion of ressentiment as it can be applied to contemporary conspiracism. The effectiveness of this comparative assessment thus raises the question of
J.W. Olson
wiley   +1 more source

Importance of a Rapid and Accurate Diagnosis in Strongyloides Stercoralis and Human T-Lymphotropic Virus 1 Co-infection: A Case Report and Review of the Literature [PDF]

open access: yes, 2017
Strongyloides (S.) stercoralis and Human T-Lymphotropic Virus 1 (HTLV-1) share some endemic regions such as Japan, Jamaica, and South America and are mostly diagnosed elsewhere in immigrants from endemic areas.
Avagnina, Alejandra   +7 more
core   +2 more sources

Drivers of Noncompliance With Vaccine Mandates—The Interplay Between Distrust, Rationality, Morality, and Social Motivation

open access: yesRegulation &Governance, EarlyView.
ABSTRACT COVID‐19 amplified the issue of public resistance to government vaccination programs. Little attention has focused on people's moral reasons for noncompliance, which differ from—but often build upon—the epistemic claims they make about vaccine safety and efficacy, disease severity, and the trustworthiness of government. This study explores the
Katie Attwell   +4 more
wiley   +1 more source

Lack of efficacy of standard doses of ivermectin in severe COVID-19 patients.

open access: yesPLoS ONE, 2020
Ivermectin has recently shown efficacy against SARS-CoV-2 in-vitro. We retrospectively reviewed severe COVID-19 patients receiving standard doses of ivermectin and we compared clinical and microbiological outcomes with a similar group of patients not ...
Daniel Camprubí   +8 more
doaj   +1 more source

Human infection with Gongylonema pulchrum [PDF]

open access: yes, 1994
A 43 year old woman developed a painful tumor at the left buccal mucosa. Following local anti-inflammatory treatment a 35 mm long, living female adult worm of Gongylonema pulchrum was extracted from the affected side.
Jelinek, Thomas, Löscher, Thomas
core  

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