Results 91 to 100 of about 47,997 (240)

Molecular basis for a pore block of Tentonin 3 expressed in HEK293 cells by a conopeptide, NMB‐1

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Tentonin 3 (TTN3/TMEM150C) is a mechanosensitive ion channel that plays critical roles in mechanotransduction processes. TTN3 forms a tetramer with a predicted rectangular shape and a central pore. A conotoxin ρ‐TIA and its synthetic analog, noxious mechanosensation blocker 1 (NMB‐1), were initially developed to inhibit slowly ...
Sujin Lim   +10 more
wiley   +1 more source

The Appreciation Game. A Monist Ontology of Works of Art

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract A pluralist ontology of art states that works of art can belong to distinct ontological categories whereas a monist ontology states that all works of art belong to one ontological category. A monist ontology would be preferable since it is more informative about the nature of art, and may pave the way for a definition of art.
Enrico Terrone
wiley   +1 more source

Anemia‐associated mutations disrupt the CDIN1‐Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA‐I) disease

open access: yesThe FEBS Journal, EarlyView.
Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal   +8 more
wiley   +1 more source

Thirty Years of Autologous Platelet Concentrates: From Platelet‐Rich Plasma to Platelet‐Rich Fibrin

open access: yesJournal of Periodontal Research, EarlyView.
This review highlights the 30 years of evolution of APCs, with a focus on their clinical applications and recent technological advancements. ABSTRACT Nearly three decades have now passed since autologous platelet concentrates (APCs) were introduced into clinical practice.
Richard J. Miron   +7 more
wiley   +1 more source

Multivariate Attention-Based Orbit Uncertainty Propagation and Orbit Determination Method for Earth–Jupiter Transfer

open access: yesApplied Sciences
Current orbit uncertainty propagation (OUP) and orbit determination (OD) methods suffer from drawbacks related to high computational burden, limiting their applications in deep space missions.
Zhe Zhang, Yishuai Shi, Hongwei Han
doaj   +1 more source

Planetas en el universo [PDF]

open access: yes, 1998
Presentamos de forma comparativa las características generales y las propiedades fundamentales de nuestro Sistema Solar, así como las teorías en curso sobre el origen de los planetas y satélites.
SÁNCHEZ LAVEGA, Agustín
core  

30 Years of Enamel Matrix Derivative (EMD): Biological Foundations and Systematic Review With Meta‐Analyses Across Multiple Clinical Indications

open access: yesJournal of Periodontal Research, EarlyView.
EMD is one of the few biological agents with human histologic evidence supporting periodontal regeneration. This is reflected in improved clinical outcomes when used in regenerative surgery for intrabony defects. Despite its biological plausibility for broader therapeutic applications, further high‐quality randomized clinical trials are needed to ...
Richard J. Miron   +10 more
wiley   +1 more source

Sacerdocio femenino romano, mancha y tabú: estado de la cuestión [PDF]

open access: yes, 2014
Las Vestales y la flamínica "Dialis" eran las sacerdotisas más importantes de la religión romana; el hecho de ser mujer y a su vez, estar en el ámbito religioso, les permitía participar del estado, obteniendo ciertos privilegios de los que el resto de ...
Aguiar Esteban, Guillermo
core  

Complex demographic, developmental, fitness, and physiological responses of larval eastern hellbenders to elevated water conductivity

open access: yesJournal of Zoology, EarlyView.
Here we explore the effects of elevated water conductivity on larval eastern hellbenders (Cryptobranchus a. alleganiensis), both lethal and sublethal. We found that elevated water conductivity significantly impacts both survival and morphology, though it has limited effects on locomotor performance, stress physiology, and oxidative stress.
S. C. Mathes   +6 more
wiley   +1 more source

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