FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The study of redistribution in residual stresses during fatigue crack growth
Journal of Mechanical Engineering and Sciences, 2021 Numerical and experimental study was conducted on fatigue crack growth (FCG) of metallic components to investigate the redistribution of mechanical residual stresses during FCG.
M. Noghabi +2 more
doaj
Marine Shaft Steels (AISI 4140 and AISI 5120) Predicted Fracture Toughness by FE Simulation
Medžiagotyra, 2017 Optimal selection of material can be considered as one of the most critical steps in engineering design process. That is especially emphasized when dealing with constructions that operate in marine environment; high stresses and harsh operating ...
Goran VUKELIC, Josip BRNIC
doaj +1 more source
Infrared thermography study of the fatigue crack propagation [PDF]
, 2012 The work is devoted to the experimental study of heat dissipation process caused by fatigue crack propagation. To investigate a spatial and time temperature evolution at the crack tip set of experiments was carried out using specimens with pre-grown ...
Bannikov, M.V. +4 more
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Application of the J-Integral and Digital Image Correlation (DIC) to Determination of Multiple Crack Propagation Law of UHPC under Flexural Cyclic Loading. [PDF]
Materials (Basel), 2022 Niu Y +5 more
europepmc +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
A calculation method for limit load of the gas pipelines with girth weld surface cracks
Natural Gas Industry B, 2019 In this paper, a finite element model with girth weld defects considering crack tip singularity was established in order to facilitate the accurate and rapid safety assessment on girth weld defects of long distance gas Transmission pipeline.
Xu Wang, Jian Shuai
doaj +1 more source
Comparison of J Integral Assessments for Cracked Plates and Pipes. [PDF]
Materials (Basel), 2021 Gajdoš Ľ +3 more
europepmc +1 more source
Antiplane-inplane shear mode delamination between two second-order shear deformable composite plates [PDF]
, 2016 The second-order laminated plate theory is utilized in this work to analyze orthotropic composite plates with asymmetric delamination. First, a displacement field satisfying the system of exact kinematic conditions is presented by developing a double ...
Szekrényes, András
core +1 more source