Results 101 to 110 of about 22,962,330 (351)
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Experimental Determination and Numerical Calculation of Fracture Viscosity Criterion (J-integral)
The paper shows that it is necessary to accept energy J-integral criterion as a criterion of fracture viscosity under conditions when the zone of plasticity is rather large at crack top.
V. N. Kovalevsky +3 more
doaj +1 more source
Effects of Fixture Configurations and Weld Strength Mismatch on J-Integral Calculation Procedure for SE(B) Specimens. [PDF]
Štefane P +5 more
europepmc +1 more source
Correlation between the pivot node concept and fatigue crack closure [PDF]
The study of fatigue crack growth has been commonly done by means of bi-dimensional models and assuming a homogeneous behaviour through the thickness. According to the specimen thickness, a state of plane stress or plane strain is presumed.
Camas, Daniel +2 more
core
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Considering the residual stress, residual strain and residual strain energy, the influence of shot peening on the J-integral parameters of semi-elliptic surface crack front was quantitatively calculated and analyzed.
HOU Shuai +3 more
doaj +1 more source
Fracture mechanics analysis of damaged turbine rotor discs using finite element method [PDF]
This paper presents evaluation fracture mechanics parameters in low pressure turbine components. Critical locations such as keyway and dovetail area are experiencing stress concentration leading to crack initiation. Stress intensity factors were
Bakić Gordana M. +5 more
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A proposed approach to the application of nonlinear irreversible thermodynamics to fracture in composite materials [PDF]
The fracture criteria upon which most fracture mechanics is based involves an energy balance that is not appropriate for the fracture mechanics of viscoelastic materials such as polymer matrix composites.
Lindenmeyer, P. H.
core +1 more source

