Results 1 to 10 of about 9,608 (178)
Mortality trends in people with disabilities before and during the COVID-19 pandemic in South Korea, 2017–2022 [PDF]
Front Public HealthObjective To investigate temporal trends in mortality rates and underlying causes of death in persons with disabilities before and during the coronavirus disease 2019 (COVID-19) pandemic.
Ye-Soon Kim +5 more
semanticscholar +4 more sources
Clozapine N-oxide, compound 21, and JHU37160 do not influence effortful reward-seeking behavior in mice [PDF]
Psychopharmacology (Berl), 2023 Rationale Clozapine N-oxide (CNO) has been developed as a ligand to selectively activate designer receptors exclusively activated by designer drugs (DREADDs).
Yoshiatsu Aomine +5 more
semanticscholar +2 more sources
A head-to-head comparison of two DREADD agonists for suppressing operant behavior in rats via VTA dopamine neuron inhibition [PDF]
Psychopharmacology (Berl), 2023 Rationale Designer receptors exclusively activated by designer drugs (DREADDs) are a tool for “remote control” of defined neuronal populations during behavior.
K. Lawson, C. Ruiz, S. Mahler
semanticscholar +2 more sources
Chemogenetic activation of hypoglossal motoneurons in a mouse model of Pompe disease.
J Neurophysiol, 2022 Pompe disease is a lysosomal storage disease resulting from absence or deficiency of acid α-glucosidase (GAA). Tongue related disorders including dysarthria, dysphagia, and obstructive sleep apnea are common in Pompe disease. Our purpose was to determine
Michele L. Singer +5 more
semanticscholar +2 more sources
The Effect of DREADD Activation of Leptin Receptor Positive Neurons in the Nucleus of the Solitary Tract on Sleep Disordered Breathing [PDF]
Int J Mol Sci, 2021 Obstructive sleep apnea (OSA) is recurrent obstruction of the upper airway due to the loss of upper airway muscle tone during sleep. OSA is highly prevalent, especially in obesity. There is no pharmacotherapy for OSA.
M. Amorim +7 more
semanticscholar +2 more sources
Histopathological Findings of Lung Cancer in Black Coal Miners in the Czech Republic [PDF]
Eur J Public Health, 2022 Background Coal miners with coal workers’ pneumoconiosis (CWP, J60 according to ICD-10) were previously found to have a significantly higher risk of lung carcinoma compared to the general male population.
H. Tomášková +7 more
semanticscholar +2 more sources
DREADD Approach to Treatment of Sleep Disordered Breathing. [PDF]
Am J Respir Crit Care Med, 2020 RATIONALE Obstructive sleep apnea is recurrent upper airway obstruction caused by a loss of upper airway muscle tone during sleep. The main goal of our study was to determine if designer receptor exclusively activated by designer drugs (DREADD) could be ...
T. Fleury Curado +17 more
semanticscholar +2 more sources
Water, 2023 The development height and settlement prediction of water-conducting fracture zones caused by coal seam mining play an important role in the stability of overburden aquifers and the safety of roadways.
Jinjun Li +4 more
semanticscholar +1 more source
Addiction Biology, 2023 Relapse to oxycodone seeking progressively increases after abstinence in rats, a phenomenon termed incubation of oxycodone craving. We have previously shown that the orbitofrontal cortex (OFC) plays a critical role in incubation of oxycodone craving in ...
Adedayo Olaniran +6 more
semanticscholar +1 more source
Computer-Aided Design and Applications, 2023 . In the new normal economic development environment, strengthening human resource management to obtain core competitive advantages is of key significance for enterprises to cope with market competition and obtain economic benefits.
Junxin Chang, Shuo Wang, Quan-sheng Li
semanticscholar +1 more source