Results 91 to 100 of about 3,915,925 (244)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Comparison of J Integral Assessments for Cracked Plates and Pipes. [PDF]

open access: yesMaterials (Basel), 2021
Gajdoš Ľ   +3 more
europepmc   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Effect of Strain Hardening on the Estimation of J-Integral in Compact Tension Specimens

open access: yesJournal of King Saud University: Engineering Sciences, 2004
Compact tension (CT) specimen testing is used to compute the fracture toughness parameter J-integral for different materials using load-displacement curve. In this work, J is investigated for compact tension specimen for a strain-hardening material using
A. Al-Abduljabbar
doaj   +1 more source

Integral Cayley graphs and groups [PDF]

open access: yes, 2013
We solve two open problems regarding the classification of certain classes of Cayley graphs with integer eigenvalues. We first classify all finite groups that have a "non-trivial" Cayley graph with integer eigenvalues, thus solving a problem proposed by ...
Ahmady, Azhvan   +2 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Analisis J-integral Dengan Adventure System

open access: yesJurnal Energi Dan Manufaktur, 2015
Abstrak : ADVENTURE (ADVanced ENgineering analysis Tools for Ulra large Real world) adalah proyekambisius Jepang yang menggunakan "komputer tercepat di dunia 30-100 TFLOPS pada tahun2002", tapi juga digunakan untuk analisis GeoFEM yang dirancang untuk ...
Irsyadi Yani
doaj  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A J-INTEGRAL MEASUREMENT METHOD BASED ON DIGITAL IMAGE CORRELATION

open access: yesJixie qiangdu, 2018
J-integral is an important fracture parameter which quantitatively describes the stress and strain fields near a crack tip. Accurate and efficient measurement of J-integral is of great significance for the evaluation of crack stability and propagation in
JIANG Wei, JIANG XianFeng, HUANG YuLong
doaj  

Home - About - Disclaimer - Privacy