Results 31 to 40 of about 958,890 (240)
JAK–STAT signaling pathway in the pathogenesis of atopic dermatitis: An updated review
Frontiers in Immunology, 2022 Atopic dermatitis (AD) is a chronic, inflammatory, pruritic form of dermatosis with heterogeneous manifestations that can substantially affect patients' quality of life. AD has a complex pathogenesis, making treatment challenging for dermatologists.
I-Hsin Huang +3 more
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Emerging Topical and Systemic JAK Inhibitors in Dermatology [PDF]
, 2019 Accumulating data on cellular and molecular pathways help to develop novel therapeutic strategies in skin inflammation and autoimmunity. Examples are psoriasis and atopic dermatitis, two clinically and immunologically well-defined disorders.
Ghoreschi, Kamran +2 more
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Runx1 promotes the development of glioma cells by regulating JAK-STAT signalling pathway
Archives of Medical Science, 2019 Introduction Human glioma is known as the most frequent and primary malignant tumour of the central nervous system with high aggression and poor prognosis.
Yong Zhang, Qiming Xia, Jun Lin
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JAK-STAT, 2013 The endocrine cytokine leptin is mainly secreted by white adipose tissue and plasma leptin levels positively correlate with body fat mass. Via its action on neurons in the hypothalamic arcuate nucleus (ARC), leptin regulates body weight by stimulating energy expenditure and inhibiting food intake.
Peelman, Frank, Tavernier, Jan
openaire +2 more sources
International Journal of Distributed Sensor Networks, 2015 The development of the Internet of Things (IoT) technologies has enabled smart objects to communicate with each other, and various IoT methods and techniques have appeared accordingly.
Sangmin Park +4 more
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Geographical Distribution and Status of Actias Moths in Thailand
Walailak Journal of Science and Technology, 2011 Geographical distribution and status of Actias moths was assessed at 46 forest stations throughout Thailand from January 2004 to December 2006. At each station, an eighteen watt black light was operated against a white sheet from 6:00 pm to 6:00 am daily.
Surachai CHOLDUMRONGKUL +2 more
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Antioxidants, 2020 Heme oxygenase-1 (HO-1) has several important roles in hepatocytes in terms of anti-inflammation, anti-apoptosis, and antioxidant properties. Interleukin-6 (IL-6) is a pleiotropic cytokine associated with liver regeneration and protection against injury.
Kun-Chun Chiang +6 more
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Oral surveillance and JAK inhibitor safety: the theory of relativity
Nature Reviews Rheumatology, 2022 The published results of the post-marketing ORAL Surveillance study, which compared the Janus kinase (JAK) inhibitor tofacitinib with anti-TNF therapy in older patients with rheumatoid arthritis who have cardiovascular risk factors, have led to changes ...
K. Winthrop, S. Cohen
semanticscholar +1 more source
Cells, 2020 The JAK/STAT3 signaling pathway plays an essential role in various types of cancers. Activation of this pathway leads to increased tumorigenic and metastatic ability, the transition of cancer stem cells (CSCs), and chemoresistance in cancer via enhancing
W. Jin
semanticscholar +1 more source
Bivariate Distributions Underlying Responses to Ordinal Variables
Psych, 2021 The association between two ordinal variables can be expressed with a polychoric correlation coefficient. This coefficient is conventionally based on the assumption that responses to ordinal variables are generated by two underlying continuous latent ...
Laura Kolbe, Frans Oort, Suzanne Jak
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