Results 171 to 180 of about 60,957 (246)

JAK2 NP_004963.1:p.V617X [PDF]

, 2020
openaire   +1 more source

A Murine Bispecific Antibody Efficiently Redirects T Cells Against Calr Mutated Stem Cells In Vivo

American Journal of Hematology, Volume 101, Issue 4, Page 697-709, April 2026.
ABSTRACT Calreticulin (CALR) mutations are prevalent in 20%–30% of patients with BCR::ABL1‐negative myeloproliferative neoplasms (MPN). Mutant calreticulin (mutCALR), presented by the thrombopoietin receptor (MPL, also known as TPOR or CD110) on the surface of the disease‐initiating MPN progenitors, represents an ideal target for curative ...
Shengen Xiong, Tamara Wais, Cecilia Varga, Christina Schueller, Sarada Achyutuni, Robert Kralovics   +5 more
wiley   +1 more source

Identification of SDC1 as a Key Regulator and Therapeutic Target in Rheumatoid Arthritis via JAK2-STAT3 Pathway. [PDF]

Int J Rheum Dis
Cao G, Wu Z, Du Y, Dai D, Sun Y, Jia X, Cai H.   +6 more
europepmc   +1 more source

Autosomal Dominant Erythrocytosis Caused by Non‐Renal Erythropoietin (EPO) Due to EPO c.‐136 G>A Germline Mutation

American Journal of Hematology, Volume 101, Issue 4, Page 784-793, April 2026.
A novel erythropoietin (EPO) promoter mutation (c.‐136 G>A) causes autosomal dominant erythrocytosis via non‐renal expression of EPO. ABSTRACT We previously reported a five‐generation kindred with autosomal dominant erythrocytosis associated with a novel germline promoter variant in the erythropoietin (EPO) gene (EPO c.‐136 G>A).
Lucie Lanikova, Dusan Hrckulak, Veronika Zimolova, Felipe R. Lorenzo, Jihyun Song, Katerina Vecerkova, Olga Babosova, Linda Berkova, Vladimir Korinek, Steve Elliott, Josef T. Prchal   +10 more
wiley   +1 more source

ω-3 PUFAs Attenuate Postoperative Ileus by Modulating Macrophage Polarization via the JAK2/STAT3 Signaling Pathway. [PDF]

J Inflamm Res
Zhao X, Yu J, Zhang T, Zhang Y, Zhang L, Wang Y, Yi C, Pan H, Wang H, Ge M, Jiang Z, Wang G.   +11 more
europepmc   +1 more source

Successful Treatment of Refractory Disseminated Superficial Actinic Porokeratosis With Topical Ruxolitinib

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT This is the first documented case of disseminated superficial actinic porokeratosis (DSAP) successfully treated with topical ruxolitinib. The patient experienced near‐complete clearance after three months, suggesting that topical JAK inhibition may be an effective and well‐tolerated option for refractory porokeratosis.
Joe Khodeir, Paul Ohanian, Marielena Ohanian   +2 more
wiley   +1 more source

Electroacupuncture ameliorates ulcerative colitis by suppressing ferroptosis via the JAK2/STAT3 signaling pathway. [PDF]

Chin Med
Zhu T, Wan HY, Qu ZY, Zhu HK, Ji LX, Zhang J.   +5 more
europepmc   +1 more source

JAK2 Gene Rearrangement [PDF]

, 2020
openaire   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

The Intricate Dance Between Inflammation and Myeloproliferative Neoplasms: From Origins to Outcomes. [PDF]

Curr Hematol Malig Rep
Fleischman AG.
europepmc   +1 more source