Results 111 to 120 of about 24,933,173 (248)
Avicenna Journal of Medicine, 2017 Objective: We aimed to investigate the frequency of Janus kinase 2 ( JAK2) mutations in cases with chronic myeloproliferative disorders (CMDs), and the relationship between the presence of JAK2 mutation and leukocytosis and splenomegaly, retrospectively.
Ismail Yildiz, Osman Yokuş, Habip Gedik
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Jak-2 mutation frequency in patients with thrombocytosis
Caspian Journal of Internal Medicine, 2018 Background: We aimed to investigate the etiologic causes and the existence of Janus kinase 2 mutation (JAK2) in cases with thrombocytosis. Methods: In this retrospective study, patients, who were admitted to hematology clinic with thrombocytosis ...
Osman Yokus, Habip Gedik
doaj
Profile of pacritinib and its potential in the treatment of hematologic disorders
Journal of Blood Medicine, 2014 Eleftheria Hatzimichael, Evangelos Tsolas, Evangelos Briasoulis Department of Haematology, University Hospital of Ioannina, Ioannina, Greece Abstract: Pacritinib (previously known as SB-1518) is an innovative selective inhibitor of Janus kinase 2 and ...
Hatzimichael E, Tsolas E, Briasoulis E
doaj
Janus kinase 2 V617F mutation in an unrelated peripheral blood stem cell donor
Tzu Chi Medical Journal, 2019 Polycythemia vera (PV) is relatively uncommon in early adulthood, and evidence about the prevalence of the Janus kinase 2 (JAK2) V617F mutation in the general population is limited.
Shang-Hsien Yang +3 more
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Cuius, una cum annexorum problematum philosophicorum, veritatem ... Laurea gratia, Janus Mulenius Ottonianus Danus ... 11. Cal. April... propugnabitEnth. 163 ThesenTitelvariante nach VorlageDiss. med.
Mulenius, Janus
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Iraqi Journal of Hematology, 2016 Background: Myelofibrosis (MF) is largely documented by an abnormal cytokine expression, which in turn could contribute to bone marrow fibrosis, angiogenesis, and constitutional symptoms.
Shahla′a Fadhil Sabir
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Casein kinase 2 controls synapse organization and stability [PDF]
, 2013 Synapse remodeling is a local and dynamic process, requiring constant modifications of the neuronal network. Post-translational modifications, such as reversible phosphorylation by kinases and phosphatases, play a crucial role in synapse development and ...
Bulat, Victoria
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Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
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Chinese Medical Journal, 2016 Background: Recently, calreticulin (CALR) gene mutations have been identified in patients with essential thrombocythemia (ET). A high-frequency of ET cases without Janus kinase 2 (JAK2) mutations contain CALR mutations and exhibit clinical ...
Chao Sun +5 more
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iNew Medicine, EarlyView.Thin endometrium upregulates Cxcl11, which polarizes ovarian macrophages via NF‐κB/AKT, impairing ovarian function. A new uter‐ovarian signaling axis is identified. ABSTRACT Objective Thin endometrium (TE) is a recognized cause of female infertility, primarily associated with impaired uterine receptivity.
Yulu Yang +8 more
wiley +1 more source