Results 281 to 290 of about 457,473 (371)

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

MicroRNA-216a inhibits pancreatic cancer by directly targeting Janus kinase 2.

Oncology Report, 2014
Siliang Wang, Xiaodong Chen, M. Tang
semanticscholar   +1 more source

Janus kinase-2 (JAK2; JAK-2); SNP rs10974944 [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Extracellular vesicles released from melanoma cells constitutively expressing MHC class II promote immune evasion and cancer progression

The FEBS Journal, EarlyView.
Here, we report the role of extracellular vesicles (EVs) released from melanoma cells constitutively expressing MHC class II in the regulation of immune cell functions and melanoma metastasis. In particular, we observed an increased localization of HLA‐DRα, CAM receptors, PD‐L1, and STAT3 signaling proteins in the EVs.
Francesca Costantini, Caterina Di Sano, Samuele Raccosta, Mauro Manno, Giovanna Barbieri   +4 more
wiley   +1 more source

Retraction of: Dexmedetomidine Exerts Brain-Protective Effects Under Cardiopulmonary Bypass Through Inhibiting the Janus Kinase 2/Signal Transducers and Activators of Transcription 3 Pathway (doi: 10.1089/jir.2019.0110). [PDF]

J Interferon Cytokine Res, 2021
europepmc   +1 more source

The Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s Encephalopathy

Drug Metabolism And Disposition, 2014
Qiang Zhang, Yan Zhang, S. Diamond, J. Boer, Jennifer J. Harris, Yu Li, M. Rupar, E. Behshad, Christine M. Gardiner, P. Collier, Phillip C. C. Liu, T. Burn, R. Wynn, G. Hollis, S. Yeleswaram   +14 more
semanticscholar   +1 more source

The emerging role of the Hippo signaling pathway in interorgan crosstalk

The FEBS Journal, EarlyView.
Hippo signaling functions as a central hub of interorgan communication. Systemic cues from the gut, adipose tissue, and skeletal muscle—including hormones, metabolites, and microbial signals—regulate YAP/TAZ activity in a tissue‐ and context‐dependent manner.
Gahyeon Song, Chaerin Lee, Eek‐hoon Jho   +2 more
wiley   +1 more source

Molecular analysis of V617F mutation in Janus kinase 2 gene of breast cancer patients. [PDF]

Saudi J Biol Sci, 2019
Karim S, Malik IR, Nazeer Q, Zaheer A, Farooq M, Mahmood N, Malik A, Asif M, Mehmood A, Khan AR, Jabbar A, Arshad M, Yousafi Q, Hussain A, Mirza Z, Iqbal MA, Rasool M.   +16 more
europepmc   +1 more source

Embryonic stem cells and nuclear transfer strategies - Present state and future prospects [PDF]

, 2000
Beier, Henning M., Wobus, Anna M., Wolf, Eckhard   +2 more
core   +1 more source

Minimal Disease Activity as A New Therapeutic Target in Atopic Dermatitis: A 5‐Year Real‐Life Experience With Dupilumab

International Journal of Dermatology, EarlyView.
ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease with significant physical and psychosocial burden. Dupilumab, a monoclonal antibody targeting IL‐4Rα, has proven to be effective for moderate‐to‐severe AD, but long‐term real‐world data remain limited.
Francesco Leo, Luca Mastorino, Luca Cangialosi, Davide Favre, Chiara Anna Fiasconaro, Yingying Liao, Federico Goso, Niccolò Siliquini, Giovanni Cavaliere, Pietro Quaglino, Simone Ribero, Michela Ortoncelli   +11 more
wiley   +1 more source