Results 171 to 180 of about 74,157 (302)

Three Janus kinase inhibitors in ulcerative colitis: is upadacitinib taking the lead? [PDF]

Intest Res
Jung YS.
europepmc   +1 more source

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source

Selective Janus kinase inhibitors exhibit different effects in murine immune aplastic anemia. [PDF]

Hemasphere
Durrani J, Feng X, Wu Z, Gao S, Manley AL, Wu L, Glass J, Patel BA, Chen J, Young NS, Groarke EM.   +10 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

The use of Janus kinase inhibitors to treat noninfectious uveitis. [PDF]

Eye (Lond)
Beckman M, Srivastava SK, Lowder CY, Baynes K, Lowe A, Sharma S.   +5 more
europepmc   +1 more source

Non‐Invasive Scalp Tape‐Strip RNA Sequencing Captures Disease Activity and Treatment‐Response Signatures in Alopecia Areata

Allergy, EarlyView.
Non‐invasive scalp tape‐strip RNA sequencing captures core immune and follicular molecular signatures in alopecia areata. Tape‐strip transcriptomic profiles reflect disease severity and treatment response to baricitinib, with concordance to scalp biopsy‐derived signatures.
Carmen Mochón‐Jiménez, Jesús Gay‐Mimbrera, Viviana Dávila‐Flores, Helen He, Jerry Zhou, Irene Rivera‐Ruiz, Pedro J. Gómez‐Arias, Juan de Luque‐Fernández, Benjamin Ungar, Emma Guttman‐Yassky, Juan Ruano   +10 more
wiley   +1 more source

Treatment of Livedoid Vasculopathy with the Janus Kinase Inhibitors: A Case Series. [PDF]

Case Rep Dermatol
Zhao G, Liu Y, Ni J, Song Z.
europepmc   +1 more source

Early Epidemiologic and Immune Predictors of Atopic Dermatitis: Reduced Cord Blood Regulatory B10 Cells in the Munich Atopy Prediction Study (MAPS)

Allergy, EarlyView.
In this prospective birth cohort from Munich, comprehensive clinical assessments and longitudinal lifestyle questionnaires were combined with cord blood immune profiling. Infants who later developed AD showed altered cord blood immune signatures, including reduced CD4+ T cells, increased B cells and markedly decreased Breg cells. Epidemiologic factors,
S. Preis, S. Kaesler, M. Koeberle, M. Hils, B. Evers, R. L. Silva, Y. Skabytska, L. Schellenberger, H. Hufnagel, M. Schielein, B. Kuschel, Y. Amar, A. Zink, T. Biedermann, Z. Kurgyis   +14 more
wiley   +1 more source

Management of Pregnancy in Women with Inflammatory Bowel Disease: Positioning Janus Kinase Inhibitors Within Current Evidence. [PDF]

Curr Issues Mol Biol
Colacurci D, Pellegrino R, Lamart A, Staiano D, De Costanzo I, Izzo M, Imperio G, Landa F, Scamardella G, Di Lella E, Federico A, Sarno L, Gravina AG.   +12 more
europepmc   +1 more source

Research progress in electrochemical determination of Janus kinase inhibitors and proposals for amplifying clinical applicability. [PDF]

Mikrochim Acta
Mikus P, Hanko M, Zelinkova Z, Labuda J.
europepmc   +1 more source