Results 201 to 210 of about 55,676 (335)

Marine Bioactive Molecules as Inhibitors of the Janus Kinases: A Comparative Molecular Docking and Molecular Dynamics Simulation Approach. [PDF]

Curr Issues Mol Biol
Ahmed EA, Abdelsalam SA.
europepmc   +1 more source

B Cell Acute Lymphoblastic Leukemia is Driven by Activating Janus Kinase Mutations Cooperating with Spi1 and Spib Deletions in a Murine Model

, 2020
Michelle Lim
openalex   +1 more source

“Nomen Omen: The Myth of God Janus”

JEADV Clinical Practice, EarlyView.
Alba Guglielmo
wiley   +1 more source

Mechanosensitive Cell‐Laden Shape‐Memory Scaffolds Engineered via Cryogelation

Small Structures, EarlyView.
GelMA‐based shape‐memory scaffolds encapsulating human adipose‐derived stem cells are fabricated via cryogelation, showing rapid recovery and high cell viability. Under cyclic compression, they promoted mechanotransduction gene expression, and composite formulations (collagen/GelMA, dECM/GelMA) retained robust shape‐memory, highlighting their promise ...
JaeYoon Lee, ByungJoon Choi, Hanjun Hwangbo, GaEun Heo, GeunHyung Kim   +4 more
wiley   +1 more source

Systematic review of Janus kinases inhibitors for rheumatoid arthritis: methodology, reporting, and quality of evidence evaluation. [PDF]

Front Pharmacol
Shen X, Liu X, Guo X, Hou X, Huang H, Feng Z.   +5 more
europepmc   +1 more source

Anisodamine Maintains the Stability of Intervertebral Disc Tissue by Inhibiting the Senescence of Nucleus Pulposus Cells and Degradation of Extracellular Matrix via Interleukin-6/Janus Kinases/Signal Transducer and Activator of Transcription 3 Pathway. [PDF]

Front Pharmacol, 2020
Tang N, Dong Y, Chen C, Zhao H.
europepmc   +1 more source

Adapter Protein Shc Regulates Janus Kinase 3 Phosphorylation [PDF]

, 2014
Jayshree Mishra, Narendra Kumar
openalex   +1 more source

Integrated multi‐omics analysis reveals metabolic reprogramming as a key driver of angiotensin II‐induced vascular remodeling

VIEW, EarlyView.
This study investigates the molecular alterations underlying angiotensin II (Ang II)‐induced vascular remodeling in cardiovascular diseases using a multi‐omics approach. Through data exploration and integrated multi‐omics analysis, our findings reveal that Ang II‐driven vascular injury in vascular smooth muscle cells is mediated by metabolic ...
Yiwei Hu, Dan Zhao, Lingyan Zhong, Jianxujie Zheng, Dongxue Zhang, Enhui Wu, Qian Shi, Liang Qiao, Ling Lin   +8 more
wiley   +1 more source

Sometimes Small Is Beautiful: Discovery of the Janus Kinases (JAK) and Signal Transducer and Activator of Transcription (STAT) Pathways and the Initial Development of JAK Inhibitors for IBD Treatment. [PDF]

Dig Dis Sci
Kaunitz JD.
europepmc   +1 more source

Clinical Characteristics and Risk Factors for Cutaneous Manifestations Associated With Nemolizumab in Atopic Dermatitis: A Multicenter Retrospective Study in Japan

The Journal of Dermatology, EarlyView.
ABSTRACT Nemolizumab, an anti‐interleukin‐31 receptor A monoclonal antibody, has been approved in Japan for treating atopic dermatitis (AD)‐associated pruritus. While it is effective for itch control, nemolizumab‐associated cutaneous adverse events have been increasingly recognized, yet their clinical features remain poorly characterized. In this study,
Wataru Sasaki, Ryo Saito, Kenta Suzuki, Daisuke Watanabe, Masako Minami‐Hori, Hirofumi Kamada, Hiroo Amano, Akihiko Uchiyama, Sei‐ichiro Motegi, Machiko Kamura, Kazunari Sugita, Noriko Kubota, Toshifumi Nomura, Maki Ozawa, Toshiya Takahashi, Takashi Yamakita, Kazumitsu Sugiura, Tetsuharu Ikegami, Ken Igawa, Yuka Kimura, Yoko Kataoka, Ryoichi Kamide, Masakazu Takahashi, Akio Tanaka, Mariko Sugawara‐Mikami   +24 more
wiley   +1 more source