Results 201 to 210 of about 51,902 (295)
Regulation of Janus kinases by SOCS proteins. [PDF]
Kershaw NJ +4 more
europepmc +1 more source
Schematic pathway diagram illustrating the effects of JI‐CJ002 and dabrafenib on melanoma progression. The combination of JI‐CJ002 and dabrafenib is associated with reduced B7‐H3 expression and modulation of signaling pathways implicated in melanoma progression, including JAK2/STAT3, PI3K/AKT/mTOR, and Rb/E2F1.
Sang‐Eun Lee +4 more
wiley +1 more source
Multifunctional Role of Mitochondrial Fatty Acid Oxidation in Cancer Immunotherapy and Aging
Recent studies have highlighted the complex interplay between tumor immunity, aging, and inflammation. Mitochondrial FAO is a major hub of this physiological interplay. ABSTRACT Recent studies have demonstrated the intricate relationship between tumor immunity, aging, and inflammation.
Koji Kitaoka +4 more
wiley +1 more source
Janus kinases: an ideal target for the treatment of autoimmune diseases. [PDF]
Gadina M.
europepmc +1 more source
Eliminative signaling by Janus kinases: role in the downregulation of associated receptors. [PDF]
Carbone CJ, Fuchs SY.
europepmc +1 more source
Patient‐reported outcomes are an important complement to physician‐assessed clinical outcome measures in Chronic Hand Eczema. In a pooled analysis of two randomised, controlled trials, twice‐daily treatment with delgocitinib cream 20 mg/g significantly improved the health‐related quality of life of patients with moderate to severe Chronic Hand Eczema ...
Andrea Bauer +7 more
wiley +1 more source

