Results 81 to 90 of about 1,229,192 (296)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Sedentary Behavior and Health Consequences: A Systematic Scoping Review of Prospective and Longitudinal Studies in Japan

open access: yesJournal of Epidemiology
Objectives: This scoping review summarizes and evaluates evidence from Japan on prospective relationships of sedentary behavior (too much sitting, as distinct from too little physical activity) with health outcomes, forming the basis for Japan’s new ...
Ai Shibata   +3 more
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Japanese encephalitis [PDF]

open access: yesCanadian Medical Association Journal, 2018
Li-Ta, Keng, Lih-Yu, Chang
openaire   +2 more sources

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Generic and vague uses of a second-person singular pronoun in an open-class person-reference system and speaker creativity in reported speech: the case of anata in Japanese

open access: yesLinguistics
This study analyzes hitherto neglected uses of a second-person singular (2sg hereafter) pronoun in Japanese: the ‘generic’ and ‘vague’ uses of the 2sg pronoun anata observed in reported speech. The aim of the study is twofold.
Yonezawa Yoko
doaj   +1 more source

Turning Japanese, Turning Japanese American

open access: yesThe AnaChronisT, 2004
This article examines the identity of the Sansei (third-generation Japanese Americans) as connected to their place of heritage - Japan. Focusing on David Mura's Turning Japanese: Memoirs of a Sansei (1991), we shall explore how a Sansei writer gains further understanding and realization of his ethnic identity as a Japanese American in multi-ethnic ...
openaire   +2 more sources

<p>Clustering of Lifestyle Factors and Its Association with Low Back Pain: A Cross-Sectional Study of Over 400,000 Japanese Adults</p>

open access: gold, 2020
Takahiko Yoshimoto   +6 more
openalex   +2 more sources

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