An Advax-Adjuvanted Inactivated Cell-Culture Derived Japanese Encephalitis Vaccine Induces Broadly Neutralising Anti-Flavivirus Antibodies, Robust Cellular Immunity and Provides Single Dose Protection. [PDF]
ccJE+Advax is an inactivated cell culture Japanese encephalitis (JE) vaccine formulated with Advax, a novel polysaccharide adjuvant based on delta inulin. This vaccine has previously shown promise in murine and equine studies and the current study sought
Komiya T +3 more
europepmc +4 more sources
Study of the association of seventeen single nucleotide polymorphisms and their haplotypes in the TNF-α, IL-2, IL-4 and IL-10 genes with the antibody response to inactivated Japanese encephalitis vaccine. [PDF]
To investigate whether the TNF-α, IL-2, IL-4 and IL-10 genes contribute to variations in vaccine-induced immune responses after immunization with the inactivated Japanese encephalitis vaccine (IJEV), a total of 369 individuals who received the IJEV were ...
Yao Y +11 more
europepmc +4 more sources
HLA Class II Genes HLA-DRB1, HLA-DPB1, and HLA-DQB1 Are Associated With the Antibody Response to Inactivated Japanese Encephalitis Vaccine. [PDF]
Aim: The objective of this study was to evaluate the association of the human leukocyte antigen (HLA) class II genes HLA-DRB1, HLA-DPB1, and HLA-DQB1 with the humoral immune response elicited by inactivated Japanese encephalitis (JE) vaccine (IJEV ...
Yao Y +8 more
europepmc +3 more sources
Japanese encephalitis vaccine-specific envelope protein E138K mutation does not attenuate virulence of West Nile virus. [PDF]
West Nile (WNV) and Japanese encephalitis viruses (JEV) are closely related, mosquito-borne neurotropic flaviviruses. Although there are no licensed human vaccines for WNV, JEV has multiple human vaccines, including the live, attenuated vaccine SA14-14-2.
Kaiser JA +6 more
europepmc +4 more sources
Safety profile of Japanese encephalitis vaccines: a comprehensive analysis of vaccine adverse event reports from 1993 to 2025 [PDF]
ObjectivesJapanese encephalitis is a severe mosquito-borne disease requiring effective prevention and ongoing vaccine safety monitoring. This study aimed to analyze the characteristics, severity, and reporting trends of adverse events associated with ...
Fujun Liu +5 more
doaj +2 more sources
Lessons Learned from the Japanese Encephalitis Vaccine Introduction in India That Supported the Introduction of Ivermectin-Diethylcarbamazine-Albendazole for Lymphatic Filariasis Elimination. [PDF]
. We used the introduction of the Japanese encephalitis (JE) vaccine in India as an example to understand more fully the process of introducing any new clinical product in India.
Ghosh RS, Haldar P, Jacobson J.
europepmc +2 more sources
Use of Japanese Encephalitis Vaccine in US Travel Medicine Practices in Global TravEpiNet [PDF]
Few data regarding the use of Japanese encephalitis (JE) vaccine in clinical practice are available. We identified 711 travelers at higher risk and 7,578 travelers at lower risk for JE who were seen at US Global TravEpiNet sites from September of 2009 to
Bhushan R. Deshpande +9 more
core +2 more sources
Japanese Encephalitis Vaccine: Recommendations of the Advisory Committee on Immunization Practices. [PDF]
Summary This report updates the 2010 recommendations from the CDC Advisory Committee on Immunization Practices (ACIP) regarding prevention of Japanese encephalitis (JE) among U.S.
Hills SL +4 more
europepmc +2 more sources
Persistence of IgM Antibodies after Vaccination with Live Attenuated Japanese Encephalitis Vaccine. [PDF]
. Japanese encephalitis (JE) is a vaccine-preventable, mosquito-borne disease. Substantial progress with JE control in Asia has been made during the past decade, with most endemic countries now having JE vaccination programs, commonly using live ...
Hills SL +7 more
europepmc +2 more sources
A Chimeric Japanese Encephalitis Vaccine Protects against Lethal Yellow Fever Virus Infection without Inducing Neutralizing Antibodies. [PDF]
Efficient and safe vaccines against yellow fever (e.g., YFV-17D) that provide long-lasting protection by rapidly inducing neutralizing antibody responses exist. However, the vaccine supply cannot cope with an increasing demand posed by urban outbreaks in
Mishra N +6 more
europepmc +2 more sources

