Results 51 to 60 of about 23,000 (252)

Incidence of Japanese Encephalitis and Acute Encephalitis Syndrome Hospitalizations in the Medium-Endemic Region in Central India

Journal of Epidemiology and Global Health, 2023
Background We estimated the incidence of Japanese encephalitis (JE) and acute encephalitis syndrome (AES) following routine immunization with the live-attenuated SA 14-14-2 JE vaccine.
Babasaheb V. Tandale, Pravin S. Deshmukh, Shilpa J. Tomar, Rahul Narang, Mohiuddin S. Qazi, Padmaja Goteti Venkata, Manish Jain, Dipty Jain, Vijay Kumar Guduru, Jyoti Jain, Rajesh V. Gosavi, Chandra Sekhar Valupadas, Pradeep R. Deshmukh, Abhishek V. Raut, Uday W. Narlawar, Punam Kumari Jha, Vijay P. Bondre, Gajanan N. Sapkal, Rekha G. Damle, Poornima M. Khude, Abhimanyu K. Niswade, Manoj Talapalliwar, Pragati Rathod, Padmini Soujanya Balla, Pavan Kumar Muttineni, Kishore Kumar Kalepally Janakiram, Shekhar S. Rajderkar   +26 more
doaj   +1 more source

The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker [PDF]

, 2013
The flavivirus nonstructural glycoprotein NS1 is an enigmatic protein whose structure and mechanistic function have remained somewhat elusive ever since it was first reported in 1970 as a viral antigen circulating in the sera of dengue-infected patients.
Muller, David A., Young, Paul R.
core   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

Immunization with Heterologous Flaviviruses Protective Against Fatal West Nile Encephalitis

Emerging Infectious Diseases, 2002
Prior immunization of hamsters with three heterologous flaviviruses (Japanese encephalitis virus [JEV] SA14-2-8 vaccine, wild-type St. Louis encephalitis virus [SLEV], and Yellow fever virus [YFV] 17D vaccine) reduces the severity of subsequent West Nile
Robert B. Tesh, Amelia P.A. Travassos da Rosa, Hilda Guzman, Tais P. Araujo, Shu-Yuan Xiao   +4 more
doaj   +1 more source

Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review

Clinical Anatomy, EarlyView.
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley   +1 more source

Novel applications of the tomato microbiome: Roles and considerations for agriculture, human health, and society

PLANTS, PEOPLE, PLANET, EarlyView.
Plants, like humans, have a microbiome that helps them grow, defend themselves against pathogens, acquire nutrients, and protect themselves against environmental stresses. The microbiome of tomatoes, a staple crop grown worldwide, could be utilized not only to reduce fertilizer and pesticide applications, but also to clean up harmful pollutants ...
Sean Lindert, Kathryn Kingsley, Peerapol Chiaranunt, James F. White   +3 more
wiley   +1 more source

Effectiveness of Japanese encephalitis SA 14-14-2 live attenuated vaccine among Indian children: Retrospective 1:4 matched case-control study

Journal of Infection and Public Health, 2018
Objectives: We estimate the effectiveness of Japanese encephalitis (JE) SA 14-14-2 live-attenuated vaccination single dose campaign among children aged 1–15 years in India during 2006–07.
Babasaheb V. Tandale, Siraj A. Khan, Komal P. Kushwaha, Helina Rahman, Milind M. Gore, Gajanan N. Sapkal, Vijay P. Bondre, D.K. Srivastava, Basanta Laskar, J. Mahanta   +9 more
doaj   +1 more source

A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis [PDF]

, 2017
The structural flexibility or 'breathing' of the envelope (E) protein of flaviviruses allows virions to sample an ensemble of conformations at equilibrium.
Diamond, Michael S, Dowd, Kimberly A, Goo, Leslie, Pierson, Theodore C, VanBlargan, Laura A   +4 more
core   +5 more sources

Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley   +1 more source

Development of a vaccine to prevent Japanese encephalitis: a brief review

International Journal of General Medicine, 2009
Viroj WiwanitkitWiwanitkit House, Bangkhae, Bangkok, ThailandAbstract: Japanese encephalitis (ICD 10: A83.0) is an important specific viral encephalitis caused by the Japanese encephalitis virus, a virus of the Flavivirus group.
Viroj Wiwanitkit
doaj