Results 131 to 140 of about 58,844 (318)

Extinction of JC virus tumor-antigen expression in glial cell--fibroblast hybrids. [PDF]

, 1988
Alan H. Beggs, Richard J. Frisque, George Scangos   +2 more
openalex   +1 more source

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

Cancer Communications, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang, Feng Liu, Dan Cui, Caixia Xu, Jiachang Chi, Tinghua Yan, Fang Guo   +6 more
wiley   +1 more source

Progressive multifocal leukoencephalopathy in a patient without apparent immunosuppression

Virology Journal, 2010
An 80-year-old man with no history of an immune-compromising disorder was diagnosed with progressive multifocal leukoencephalopathy (PML). He presented with dysphagia and left-sided weakness; magnetic resonance imaging demonstrated marked signal ...
Escobar Miguel A, Lovy Jordan, Sotelo-Rafiq Elsa P, Vaklavas Christos, Tsimberidou Apostolia M   +4 more
doaj   +1 more source

JC virus existence in Chinese gastrointestinal carcinomas

Oncology Letters, 2012
The John Cunningham virus (JCV) infects a large proportion of the population worldwide and may cause progressive multifocal leukoencephalopathy upon immunodeficiency. Recent reports provided evidence of its oncogenetic role in malignancies. In this study, JCV was examined by targeting T antigen, viral protein and agnoprotein in paraffin-embedded or ...
Yunpeng Liu, Xiang‑Hong Yang, Zuo-Zhou Wang, Pu Xia, Hua-chuan Zheng, Jian-ping Wang, Yu-Shuang Zheng, Yasuo Takano   +7 more
openaire   +4 more sources

Enhancing antitumor immunity through the combination of cholesterolized TLR7 agonist liposomes and radiotherapy: a role for IL‐1β and the inflammasome pathway

Cancer Communications, EarlyView.
Abstract Background Radiotherapy (RT) is a key treatment modality in cancer therapy, utilizing high‐energy radiation to directly kill tumor cells. Recent research has increasingly highlighted RT's potential to indirectly enhance antitumor immunity. However, this immune activation alone often fails to generate sustained systemic antitumor responses.
Xuejiao Han, Yuan Cheng, Dandan Wan, Aqu Alu, Ziqi Zhang, Zhenfei Bi, Manni Wang, Yan Tang, Weiqi Hong, Siyuan Chen, Li Chen, Yuquan Wei   +11 more
wiley   +1 more source

N6‐methyladenosine‐regulated exosome biogenesis orchestrates an immunosuppressive pre‐metastatic niche in gastric cancer peritoneal metastasis

Cancer Communications, EarlyView.
Abstract Background Gastric cancer peritoneal metastasis is clinically challenging, given the limited treatment options and poor prognosis. The molecular mechanisms that precede gastric cancer peritoneal metastasis, known as the pre‐metastatic niche (PMN), and its relationship with N6‐methyladenosine (m6A) modification remain unclear.
Song Li, Jianyuan Zhou, Shuang Wang, Qian Yang, Shulun Nie, Chunwang Ji, Xue Zhang, Shuhan Li, Xuanyu Zhou, Jiahui Chu, Xuehui Wu, Jianqiao Jiao, Ruitao Xu, Qian Xu, Miao Huang, Qiushi Wang, Liliang Dou, Qinqin Hu, Fan Jiang, Xin Dai, Zhaodi Nan, Xinyu Song, Di Zhang, Lian Liu   +23 more
wiley   +1 more source

JC virus-associated central nervous system diseases in HIV-infected patients in Brazil: Clinical presentations, associated factors with mortality and outcome

Brazilian Journal of Infectious Diseases, 2012
Introduction: Several presentations of neurologic complications caused by JC virus (JCV) in human immunodeficiency virus (HIV)-infected patients have been described and need to be distinguished from the “classic” form of progressive multifocal ...
Felipe Piza, Maria Cristina Fink, Gilberto S. Nogueira, Claudio S. Pannuti, Augusto C. Penalva de Oliveira, José Ernesto Vidal   +5 more
doaj  

Unusual DNA structure in the regulatory region of the human papovavirus JC virus [PDF]

, 1988
Sorour Amirhaeri, Franz Wohlrab, Eugene O. Major, Robert D. Wells   +3 more
openalex   +1 more source

Eugenia brasiliensis: Analysis of the Chemical Profile and Evaluation of Cytotoxic Potential

Chemistry &Biodiversity, EarlyView.
Leaves of Eugenia brasiliensis were dried, crushed and macerated with polarity increment. The antiporliferative and anti‐migratory potential and the cell cycle were evaluated. 28 compounds were tentatively identified by mass sceptrometry. ABSTRACT This work evaluated the antiproliferative potential of Eugenia brasiliensis leaf extracts against the HeLa
Giovana G. F. V. de Oliveira, Milena F. Longue, Letícia M. R. Pescinelli, Thiago S. Charret, Thalya S. R. Nogueira, Mariana T. M. Pereira, Ivo J. C. Vieira, Lucas S. Abreu, Vinicius D. B. Pascoal, Aislan C. R. F. Pascoal   +9 more
wiley   +1 more source

Detection of JC Polyomavirus tumor antigen in gastric carcinoma: a report from Iran

Iranian Journal of Microbiology, 2018
Background and Objectives: Factors contributing to development of gastric cancer are still under investigation. The JC Virus (JCV), as an oncogenic virus, has been indicated to play a possible role in gastric carcinogenesis. Theoretically, tumor antigen (
Samira Izi, Masoud Youssefi, Farzad Rahmani, Nema Mohammadian Roshan, Atefeh Yari, Farnaz Zahedi Avval   +5 more
doaj