Results 141 to 150 of about 71,442 (302)

Omics Insights Into the Effects of Highbush Blueberry and Cranberry Crop Agroecosystems on Honey Bee Health and Physiology

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Honey bees (Apis mellifera) are vital pollinators in fruit‐producing agroecosystems like highbush blueberry (HBB) and cranberry (CRA). However, their health is threatened by multiple interacting stressors, including pesticides, pathogens, and nutritional changes.
Huan Zhong   +25 more
wiley   +1 more source

Rootstock impacts on citrus flush dynamics, vegetative growth, and Diaphorina citri infestation and dispersion: Implications for huanglongbing management

open access: yesPest Management Science, EarlyView.
Dwarfing citrus rootstocks restrict flush shoot growth on the scion, thereby reducing Asian citrus psyllid infestation, dispersal, and huanglongbing (HLB) progression. These findings support the use of dwarfing rootstocks as an effective cultural strategy in integrated HLB management for citrus orchards.
Deived Uilian de Carvalho   +6 more
wiley   +1 more source

Replication of JC Virus DNA in the G144 Oligodendrocyte Cell Line Is Dependent Upon Akt

open access: yes, 2017
Progressive multifocal leukoencephalopathy (PML) is an often-fatal demyelinating disease of the central nervous system. PML results when oligodendrocytes within immunocompromised individuals are infected with the human JC virus (JCV).
Paul J. Phelan   +6 more
core   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

open access: yesPhytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan   +8 more
wiley   +1 more source

The pivotal image findings of progressive multifocal leukoencephalopathy: A case report

open access: yesTungs’ Medical Journal
Progressive multifocal leukoencephalopathy (PML) is a rare disease associated with the reactivation of the JC virus, particularly in immunocompromised patients.
Shou-De Ma   +4 more
doaj   +1 more source

Integrating infection intensity and aggregation into the dynamics of pathogens with within‐host replication

open access: yesJournal of Animal Ecology, EarlyView.
We bridge micro‐ and macroparasite theory with a model tracking pathogen load heterogeneity. By incorporating load‐dependent mortality and within‐host pathogen growth, we show how pathogen load aggregation alters disease prevalence, host suppression effects, and virulence evolution, providing insights for managing complex infectious disease like ...
Ruijiao Sun   +3 more
wiley   +1 more source

Transformation of B Lymphocytes by SV40, a small DNA tumor virus

open access: yes, 2012
For decades we have assessed the risk to humans by the monkey virus SV40, through studies in animal models and humans. While there is increase in the accumulation of opinions over its DNA sequence prevalence in certain human cancers, especially non ...
Alaribe, Franca Nneka
core  

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

open access: yesAllergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake   +8 more
wiley   +1 more source

Keratinocyte Priming by Staphylococcus aureus Reduces HSV‐1 Susceptibility

open access: yesAllergy, EarlyView.
ADEH+ patients have a reduced microbial diversity with increased S. aureus and S. epidermidis colonization compared to ADEH− and healthy controls. Heat‐killed S. aureus reduced HSV‐1 susceptibility and release of infectious progeny virus in a keratinocyte in vitro model. Heat‐killed S.
Phila Cara Baumann   +19 more
wiley   +1 more source

Magnetic Resonance Imaging Evaluation of Functional Differences Between In Vivo Human Kidneys and Discarded Human Kidneys During Ex Vivo Normothermic Machine Perfusion

open access: yesArtificial Organs, EarlyView.
Comparative MRI of in vivo kidneys and ex vivo donor kidneys during NMP revealed marked physiological differences and limited correspondence with conventional perfusion or injury metrics. These distinct ex vivo MRI signatures emphasize the need to consider parameters beyond conventional in vivo functional markers when assessing organ viability during ...
Tim L. Hamelink   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy