Results 111 to 118 of about 128,017 (118)

Radiolabeled hormones in insulin research, a minireview.

Journal of labelled compounds & radiopharmaceuticals, 2020
Preparation of both 125 I-labeled insulin and insulin-like growth factor 1 (IGF-1) was critical because it enabled a detailed characterization of binding properties of these important hormones towards their cognate transmembrane receptors.
J. Jiráček, L. Žáková, Aleš Marek
semanticscholar   +1 more source

Multipodal insulin mimetics built on adamantane or proline scaffolds.

Bioorganic chemistry (Print), 2020
Multi-orthogonal molecular scaffolds can be applied as core structures of bioactive compounds. Here, we prepared four tri-orthogonal scaffolds based on adamantane or proline skeletons.
Jan Hajduch, B. Fabre, Benjamin Klopp, R. Pohl, M. Buděšínský, Veronika Šolínová, V. Kašička, Cemal Kopruluoglu, S. M. Eyrilmez, M. Lepšík, P. Hobza, K. Mitrová, Marta Lubos, María Soledad Garre Hernández, J. Jiráček   +14 more
semanticscholar   +1 more source

Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2.

Vitamins and hormones, 2023
J. Jiráček, I. Selicharová, L. Žáková   +2 more
semanticscholar   +1 more source

A radioligand receptor binding assay for measuring of insulin secreted by MIN6 cells after stimulation with glucose, arginine, ornithine, dopamine, and serotonin

Analytical and Bioanalytical Chemistry, 2021
Seiya Asai, L. Žáková, I. Selicharová, Aleš Marek, J. Jiráček   +4 more
semanticscholar   +1 more source

A Rapid and High-Sensitivity Non-radioactive Screening Assay for Insulin Receptor Ligands

bioRxiv
Jana Staňurová, Kateřina Čermáková, D. Just, Ullrich Jahn, B. Fabre, Erik Rozkovec, L. Žáková, P. Šácha, J. Jiráček, Jan Konvalinka   +9 more
semanticscholar   +1 more source

Vesiculin reveals the role of the IGF2 C-domain in receptor specificity within the insulin-IGF system.

Protein Science
Karolína Mrzílková, Marta Lubos, Klaudie Hladoníková, I. Selicharová, J. Jiráček, Jakub Kaminský, L. Žáková   +6 more
semanticscholar   +1 more source

The Development of a Versatile Trifunctional Scaffold for Biological Applications

, 2015
V. Vaněk, J. Pícha, B. Fabre, M. Buděšínský, M. Lepšík, J. Jiráček   +5 more
semanticscholar   +1 more source

Tri-Orthogonal Scaffolds for the Solid-Phase Synthesis of Peptides

Annalen der Pharmacie, 2018
J. Pícha, B. Fabre, M. Buděšínský, Jan Hajduch, M. Abdellaoui, J. Jiráček   +5 more
semanticscholar   +1 more source