Results 71 to 80 of about 128,017 (118)

An engineered insulin analog with dual insulin and IGF-1 receptor agonism and distinct signaling. [PDF]

Sci Adv
Selicharová I, Kirk NS, Kertisová A, Lubos M, Mitrová K, Ticháčková T, Žáková L, Chrudinová M, Březinová J, Harant K, Voldřich J, Hájek M, Huffman DM, Jiráček J.   +13 more
europepmc   +1 more source

Betaine-homocysteine methyltransferase: zinc in a distorted barrel.

Structure, 2002
J. C. Evans, D. Huddler, J. Jiráček, Carmen Castro, Norman S. Millian, T. Garrow, M. Ludwig   +6 more
semanticscholar   +1 more source

Preparation and characterization of neutral trehalase for structural studies

, 2016
This study is part of a project which aim is solving the structure of the catalytic domain of neutral trehalase Nth1 from Saccharomyces cerevisiae. The main goal of this thesis is the preparation of new constructs of yeast Nth1 and optimization of their ...
Šmídová, Aneta
core  

Vale Colin Ward-A Leader in Receptor Structural Biology. [PDF]

Front Endocrinol (Lausanne), 2017
Lawrence MC, Colman PM.
europepmc   +1 more source

Insulin-like Growth Factor 1 Analogs Clicked in the C Domain: Chemical Synthesis and Biological Activities.

Journal of Medicinal Chemistry, 2017
K. Macháčková, M. Collinsová, Martina Chrudinová, I. Selicharová, J. Pícha, M. Buděšínský, V. Vaněk, L. Žáková, A. Brzozowski, J. Jiráček   +9 more
semanticscholar   +1 more source

ABEI-značené 2-5A: Způsob chemiluminiscenčního sledování vazebného procesu RNase L

, 2005
As an alternative for radiolabeled ones, chemiluminescent ABEI-labeled 2-5A probe was synthesized and evaluated for its concentration-dependent detection ...
Páv, Ondřej
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Analogues of IGF-1 for the study of interactions of the hormone with the receptors for IGF-1 and insulin

, 2018
Insulin/IGF system is a complex network of three similar hormones (insulin, IGF-1 and IGF-2) and their three similar receptors (IR-A, IR-B and IGF-1R,), which play important roles in maintaining basal energy homeostasis of the organism, in growth ...
Macháčková, Kateřina
core  

K nedožitým 90. narozeninám profesora Jiřího Jiráčka

Opera slavica, 2015
Aleš Brandner
doaj  

Jiřímu Jiráčkovi k pětaosmdesátinám

Linguistica Brunensia, 2013
Stanislav Žaža
doaj  

Molecular mechanisms in homocystinuria: spatial arrangement of human cystathionine β-synthase

, 2012
Protein misfolding is considered to be the major pathogenic mechanism in homocystinuria due to cystathionine beta-synthase (CBS) deficiency. The aim of this work was to study molecular mechanisms underlying protein misfolding of CBS mutants.
Hnízda, Aleš
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