Příprava a charakterizace nových derivátu insulinu s pozměněnou selektivitou vůči receptorům insulinu a IGF-1. [PDF]
, 2018 Insulin receptor (IR) exists in two isoforms (IR-A and IR-B), which differ in the tissue distribution and probably also in their function, i.e. in their response to insulin binding.
Halamová, Tereza
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, 2018 Insulin receptor (IR) exists in two isoforms (IR-A and IR-B), which differ in the tissue distribution and probably also in their function, i.e. in their response to insulin binding.
Halamová, Tereza
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Synthesis and biochemical characterization of hybrid analogues of human insulin and IGF-2 [PDF]
, 2013 The ever-increasing occurrence of diabetes mellitus brings about the need for development of new therapeutic agents to provide adequate treatment for patients.
Povalová, Anna
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Biologické vlastnosti konjugátů insulinu s N-acetylgalaktosaminem [PDF]
Insulin is a key regulator of glucose metabolism in the body. Deficiencies in its function lead to a severe metabolic disorder known as diabetes mellitus. For some diabetics, daily insulin administration is the only way to survive.
Kavale, Gustav
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Preparation of a new insulin analog in order to study the interaction of the hormone with insulin receptor isoforms, [PDF]
, 2016 Insulin acts as a key hormone in the blood glucose levels maintaining mechanisms. Outside this metabolic function it also has a growth hormone functionality.
Halamová, Tereza
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Novel shortened and full-length insulin analogs with modifications in the position B26
, 2007 Katedra biochemieDepartment of BiochemistryPřírodovědecká fakultaFaculty of ...
Hančlová, Ivona
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Targeting insulin storage forms in pancreatic β-cell secretory granules
, 2023 In this dissertation, we focused on a comprehensive investigation of insulin production, storage and secretion by pancreatic -cells. We successfully developed a new assay for the rapid and sensitive determination of insulin concentration in biological ...
Asai, Seiya
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Metody studia necharakterizovaných proteinů
Tato bakalářská práce se věnuje problematice proteinů s neznámou funkcí a možnostem jejich bližší charakterizace. V úvodu představuje širší kontext výzkumu lidského proteomu a zdůrazňuje význam studia proteinů, jejichž role v biologických procesech zatím
Hric, Pavol
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Study of physiological functions of betaine homocysteine S-methyltransferase and betaine homocysteine S-methyltransferase 2 [PDF]
, 2013 Betaine homocysteine S-methyltransferase (BHMT) and betaine homocysteine S-methyltransferase 2 (BHMT-2) are mammalian cytosolic metalloenzymes. They both participate in the metabolism of homocysteine (Hcy), specifically Hcy remethylation, mainly in liver
Mládková, Jana
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The synthesis of phosphonic acids derived from homocysteine via transesterification reactions
ARKIVOC, 2011 Jan Pícha +3 more
doaj +1 more source