Results 71 to 80 of about 4,434,471 (304)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Influence of Stress and Nursing Leadership on Job Satisfaction of Pediatric Intensive Care Unit Nurses [PDF]
, 2000 BACKGROUND: High levels of stress and the challenges of meeting the complex needs of critically ill children and their families can threaten job satisfaction and cause turnover in nurses.
Bratt, Marilyn Meyer +3 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
The Analysis of a Workplace From an Ergonomically Criterion. Case Study: Preliminary Charge
The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2013 This paper presents a practical method of analyzing a wokplace from an ergonomically criterion based on an "ergonomic analysis questionnaire", and, also, the conclusions and proposed measures in order to improve the activity of the analyzed workplace.
Adrian VASILIU, Marian BORDEI
doaj
DisabilitiesTransportation is integral to the employment accessibility and sustainability of people with disabilities. This study aims to identify barriers, facilitators, and solutions to commuting for people with disabilities, drawing from their perspectives as ...
Alexandra Tessier +5 more
doaj +1 more source
Unlocking success: The mediating power of organizational commitment and job satisfaction between work-life balance and employee performance [PDF]
Problems and Perspectives in ManagementWork-life balance is crucial in fostering a sense of ownership and achieving company success. When employees can achieve a good balance between work and personal lives, they are more satisfied and have higher organizational commitment. This study aims to
Ni Made Dwi Puspitawati +4 more
doaj +1 more source
Supported and Customized Employment [PDF]
, 2004 [Excerpt] Supported employment has been a service option for a long time and is responsible for many individuals working who were previously considered unemployable.
Parent, Wendy
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
پژوهان, 2018 Background and Objective: Job adjustment as a psychosocial well-being and adaptive state of the individual to post-employment occupation has positive effects, which necessitates identifying the factors that affecting it.
Sohaila Jalilian, Ghaffar Karimianpour
doaj
The Influence of Job Satisfaction and Organizational Commitment on Executive Withdrawal and Performance [PDF]
, 2000 This research examines the influence of job satisfaction and three dimensions of organizational commitment (i.e., affective, continuance, and normative) on the intention to leave, job search activity, performance, and leadership effectiveness of ...
Boswell, Wendy R. +2 more
core +1 more source