Results 61 to 70 of about 4,434,471 (304)
Travail des jeunes, une évidence pour assurer l’indépendance [PDF]
: The present recherch is emanation of the expression of the young diplomas universzitiy in démocratic republic of congo in general and those of the city of kinshasa in particular is a call to political decisoon-makers of democratic republic of congo for
TONDIKU – MBEMBI KHYM’S, YADISADILA KIKA PITSHOU & KABAKA SESEP KIMBETE SABINE
doaj
A Demonstration of Continuous Interaction with Elckerlyc [PDF]
We discuss behavior planning in the style of the SAIBA framework for continuous (as opposed to turn-based) interaction. Such interaction requires the real-time application of minor shape or timing modifications of running behavior and anticipation of ...
Reidsma, Dennis +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Introduction: Employees are regularly offered opportunities to make their work more appealing and rewarding. These opportunities might be as simple as making fine changes to their daily tasks to boost happiness and to connect with more people at vocation.
V Siva Kalyan +5 more
doaj +1 more source
The Effects of Market Survey Rates, Job Evaluation and Job Gender on Job Pay [PDF]
The present study investigates the effects of current pay, market surveys, job evaluation points, job gender, and rater sex on pay rates for jobs. 406 compensation administrators assigned new pay rates to nine jobs in one of two matched job sets: either ...
Milkovich, George T. +2 more
core +2 more sources
En el presente trabajo se generaron diversas ideas de productos y servicios enfocadas en el mercado colombiano. Cuyo objetivo es idear un producto o servicio que se adapte a las tendencias del mercado y satisfaga las necesidades de sus respectivos consumidores.
Gracia Alarcón, Iris Oriana +3 more
openaire +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source

