Results 111 to 120 of about 737,186 (350)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Particle swarm optimization applied to job shop scheduling [PDF]

, 2007
In this project we have to apply the particle swarm optimization algorithm to job shop scheduling problem. Job shop scheduling is a combinatorial optimization problem where we have to arrange the jobs which may or may not be processed in every machine in
Dwivedi , Piyush, Vishal , Vivek
core  

Mental Workload Analysis of Workers Using the Swedish Occupational Fatigue Index (SOFI) Method at A Job Shop, Sheet Metal, And Pipe Metal Manufacturing Company in Surabaya

, 2023
Mochammad Tutuk Safirin, Mega Cattleya Prameswari Anissa Islami, Rizqi Novita Sari, Sinta Dewi, Enny Aryanny   +4 more
openalex   +2 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

MODEL OPTIMASI PENJADWALAN PRODUKSI YANG TERINTEGRASI DENGAN MEMPERTIMBANGKAN FAKTOR BIAYA

Jurnal Teknik Industri, 2003
The paper discusses optimation integrated production scheduling model which is included deciding production allocation, operations regulating for job shop process and capacity planning as integrated activity.
Dian Retno Sari Dewi
doaj  

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source

On the Recursive Representation of the Permutation Flow and Job Shop Scheduling Problems and Some Extensions

Mathematics
In this paper, we propose a formulation of the permutation flow and job shop scheduling problems using special recursive functions and show its equivalence to the existing classical formulation.
Boris Kupriyanov, Alexander Lazarev, Alexander Roschin, Frank Werner   +3 more
doaj   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

Dynamic flexible job shop co-scheduling optimization based on graph neural network and deep reinforcement learning

Operations Research Perspectives
With the continuous advancement of manufacturing, job shop scheduling faces complex dynamic disturbances that pose significant challenges to production.
Lan Yang, Zhong Yang, Li Bi, Xiaogang Jiao   +3 more
doaj   +1 more source