Results 61 to 70 of about 1,299,908 (329)

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Correlation of Job Stress, Job Satisfaction, Job Motivation and Burnout and Feeling Stress

Procedia - Social and Behavioral Sciences, 2013
AbstractNowadays, existence of efficient and self-motivated human resource is one of the important issues of great importance in professional environments. Considering that human resource in an organization is one of the important resources in that organization, steps should be taken to identify weak and strong points in improving the operation of ...
Khalatbari, Javad, Ghorbanshiroudi, Shohreh, Firouzbakhsh, Mehdi   +2 more
openaire   +1 more source

The Predictor of external environment, occupational stress, job satisfaction and intent to leave towards organizational commitment [PDF]

, 2012
The purpose of this article was to determine the relationship between external environment, occupational stress, job satisfaction and intent to leave towards organizational commitment. A convenience sample group of 130 employees of Northport (Malaysia)
Hashim, Shahrin, Maalip, Halimah, Syed Alwee, Syarifah Nurul Ain, Yahaya, Azizi, Yahaya, Noordin   +4 more
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Relationship between job stress, job crafting, and job burnout among college counselors

环境与职业医学
BackgroundJob burnout has become an important factor affecting the mental and physical health and work efficiency of college counselors, and indirectly affects the quality and development of talent cultivation for college students.
Haixia ZHAO, Xue ZOU, Le HAN, Haibo ZHAO, Haiying MA   +4 more
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

The Moderating Role of Empathic Leadership in Job Crafting and Employee Engagement Among Millennial Workers Under Job Stress

Journal of Leadership in Organizations
Introduction/Main Objectives: This study aims to examine the role of job stress and employee engagement of millennial workers mediated by job crafting and moderated by empathetic leadership. Background Problems: Leadership is one of the factors that will
Bernardus Aris Ferdinan, Robertus Adi Nugroho, Jonathan Edward Pangemana   +2 more
doaj   +1 more source

PENGARUH WORK LIFE BALANCE TERHADAP KEPUASAN KERJA DENGAN STRES KERJA SEBAGAI VARIABEL INTERVENING (Studi Pada PT. BPD Kalimantan Tengah Cabang Buntok) [PDF]

This research aims to determine how the work life balance, job satisfaction, and work Stress, the effect of the work life balance on job satisfaction, the effect of work life balance on work Stress, and the effect of work Stress on job satisfaction, and ...
Riyana, Nindi Dwi
core  

An investigation of occupational stress in New Zealand dentists : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]

, 1995
The present study sought to identify the occupational stressors as well as the resultant psychological and physical stress outcomes for New Zealand dentists.
Bate, Colin
core  

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source