Results 71 to 80 of about 3,704,135 (284)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Moderating effect of social support on personal financial constraints and job stress relationship [PDF]
The aim of this paper is to examine the moderating effect of social support (which may be supervisory, friends, family and relatives) on the relationship of personal financial constraints and job stress relationship.
Rehman, Kashif-Ur- +2 more
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
The effects of job demands on job stress
Korean Journal of Industrial and Organizational Psychology, 2016 The purpose of this study was to examine the effect of job demands on job stress and the moderating effects of job control and procedural justice. Specifically, first, the job demands were divided into quantitative demands and qualitative demands, and relative effects of the two demands on job stress were compared. Second, the moderating effects of job
KwangMo Lim, Jinkook Tak
openaire +2 more sources
Empirical Analysis of Job Stress on Job Satisfaction among University Teachers in Pakistan
, 2011 This research investigates the relationship between job stress and job satisfaction among University teachers in Pakistan. Data were collected from 400 respondents from cross sectional method from all four provinces by using simple random technique.
Hashmi, Dr. Muhammad Aamir +4 more
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Prevalence And Risk Factors Of Job Strain Among Laboratory Technicians In Hospital Universiti Sains Malaysia. [PDF]
, 2004 Several sources of job stress exist.
Aziah, B.D. +4 more
core +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Job stress among nurses in Ethiopia: A systematic review and meta-analysis
International Journal of Africa Nursing SciencesBackground: Although job stress appears in all professions, jobs related to humans are associated with high levels of stress. Nurses are the most frequent medical staff who spend the largest amount of time with patients, cover all areas of the healthcare
Woldu Aberhe +6 more
doaj +1 more source