Results 61 to 70 of about 3,704,135 (284)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Investigating the Relationship between Job Fit and Job Stress and Organizational Performance of Yasuj Health Center Personnel in the West of Iran [PDF]

Journal of Community Health Research, 2023
Background: Stress of managers and employees of the organization reflected in the efficiency of the organization. The aim of this study is to investigate the relationship between job fit and stress, and organizational performance of Yasouj Health Center ...
Farnaz Shojaei, Zohreh Karimiankakolaki
doaj  

Job characteristics: their relationship to job satisfaction, stress and depression [PDF]

Journal of Psychology in Africa, 2014
This study investigated the influences of job characteristics on job satisfaction, stress and depression among South African white collar workers. Participants were managers in full-time employment with large organisations. They completed the Job Diagnostic Survey, the Perceived Stress Scale and the Beck Depression Inventory.
Renier, Steyn, Naseema, Vawda
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Mediating Effects of Job Stress on the Relationship Between Sleep Quality and Job Satisfaction Among Construction Workers [PDF]

علوم بهداشتی ایران
Background and Purpose: The construction industry creates various health risks to workers, affecting their physical and mental well-being. This study aimed to investigate the relationship between sleep quality and job satisfaction in construction workers,
Atefeh Mohammadinejad, Saied Yazdanirad, Alireza Dehdashti, Parviz Kakaei, Fatemeh Keshizadeh, Maryam Farokhzad   +5 more
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The Moderating Role of Empathic Leadership in Job Crafting and Employee Engagement Among Millennial Workers Under Job Stress

Journal of Leadership in Organizations
Introduction/Main Objectives: This study aims to examine the role of job stress and employee engagement of millennial workers mediated by job crafting and moderated by empathetic leadership. Background Problems: Leadership is one of the factors that will
Bernardus Aris Ferdinan, Robertus Adi Nugroho, Jonathan Edward Pangemana   +2 more
doaj   +1 more source

JOB-monitor 2020

, 2020
De JOB-monitor is in 2001 door Jongeren Organisatie Beroepsonderwijs (JOB) opgezet om de tevredenheid van mbo-studenten te meten. Elke twee jaar laat JOB de monitor uitvoeren door onderzoeksbureau ResearchNed.
ResearchNed
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source