Results 91 to 100 of about 6,290,196 (343)
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
International Journal of Mathematics for IndustryThis paper explores operations on fuzzy incidence graphs (FIGs), focusing on join, Cartesian product, tensor product, and composition. Emphasizing strong fuzzy incidence graphs (SFIGs), the study examines strong incidence domination (SID) and the strong ...
Kavya R. Nair, M. S. Sunitha
doaj +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
Operations on Intuitionistic Fuzzy Graph Structures
Fuzzy Information and Engineering, 2016 An intuitionistic fuzzy graph structure (IFGS) is a generalization of an intuitionistic fuzzy graph. The concept of intuitionistic fuzzy graph structure is introduced and investigated in this paper.
Muhammad Akram, Rabia Akmal
doaj +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
The G-Convexity and the G-Centroids of Composite Graphs
Mathematics, 2020 The graph centroids defined through a topological property of a graph called g-convexity found its application in various fields. They have classified under the “facility location” problem.
Prakash Veeraraghavan
doaj +1 more source
Determining Crossing Number of Join of the Discrete Graph with Two Symmetric Graphs of Order Five
Symmetry, 2019 The main aim of the paper is to give the crossing number of the join product G + D n for the disconnected graph G of order five consisting of one isolated vertex and of one vertex incident with some vertex of the three-cycle, and D n consists of n ...
M. Staš
semanticscholar +1 more source
European - North American - Russian Federation Inland ENC Harmonization Group [PDF]
, 2007 In 2003, the Inland ENC Harmonization Group (IEHG) was formed to agree upon specifications for Inland ENCs that are suitable for all known Inland ENC data requirements for safe and efficient navigation in European and North American inland waterways and ...
Alexander, Lee +4 more
core +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Entry and access : how shareability comes about [PDF]
, 2007 Shareability is a design principle that refers to how a system, interface, or device engages a group of collocated, co-present users in shared interactions around the same content (or the same object).
Hornecker, E., Marshall, P., Rogers, Y.
core