Results 81 to 90 of about 858,413 (284)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Some Results on incidence coloring, star arboricity and domination number [PDF]
Two inequalities bridging the three isolated graph invariants, incidence chromatic number, star arboricity and domination number, were established. Consequently, we deduced an upper bound and a lower bound of the incidence chromatic number for all graphs.
Shiu, Wai Chee, Sun, Pak Kiu
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Mixing of Join Point Interfaces and Feature-Oriented Programming for Modular Software Product Line
Feature-oriented programming (FOP) and aspect-oriented programming (AOP) focus are to modularize additional classes behavior and crosscutting concerns, respectively, for soft- ware evolution.
Cristian Vidal +4 more
doaj +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The irregularity of graphs under graph operations
The irregularity of a simple undirected graph G was defined by Albertson [5] as irr(G) = ∑uv∈E(G) |dG(u) − dG(v)|, where dG(u) denotes the degree of a vertex u ∈ V (G).
Abdo Hosam, Dimitrov Darko
doaj +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The Cartesian product and join are two classical operations in graphs. Let dL(G)(e) be the degree of a vertex e in line graph L(G) of a graph G. The edge versions of atom-bond connectivity (ABCe) and geometric arithmetic (GAe) indices of G are defined as
Xiujun Zhang +3 more
doaj +1 more source
Crossing number of Cartesian product of prism and path
An m-prism is the Cartesian product of an m-cycle and a path with 2 vertices. We prove that the crossing number of the join of an m-prism () and a graph with k isolated vertices is km for each We then use this result to prove that the crossing number of ...
Yip C. Yiew, Gek L. Chia, Poh-Hwa Ong
doaj +1 more source

