Results 51 to 60 of about 794,230 (296)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

On Forming Characteristics of Hems by Means of Incremental Sheet Forming

Journal of Manufacturing and Materials Processing
Given the need for versatile joining processes, form-fit joining is gaining increasing importance. Although it has known limitations and complexity, roller hemming remains widely used due to its flexibility. Here, the novel Incremental Sheet Forming (ISF)
Dennis Steinfels, David Bailly
doaj   +1 more source

Mechanical and Crack-Sensing Capabilities of Mode-I Joints with Carbon-Nanotube-Reinforced Adhesive Films under Hydrothermal Aging Conditions

Nanomaterials, 2020
The fracture behavior and crack sensing of mode-I joints with carbon nanotube (CNT)-reinforced adhesive films were explored in this paper under hydrothermal aging conditions.
Xoan F. Sánchez-Romate, Jesús Martin, María Sánchez, Alejandro Ureña   +3 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Research progress on laser joining of brittle and transparent materials

Hanjie xuebao
The joining technology of brittle and transparent materials has been widely applied in aerospace, electronic packaging, and sensor industries. Research on the joining technology of transparent materials holds significant academic and engineering ...
Rui PAN, Yinghao FENG, Pei CHEN, Shujun CHEN, Fan JIANG, Jin YANG, Peng LI   +6 more
doaj   +1 more source

Recent Progress in the Joining of Titanium Alloys to Ceramics

Metals, 2018
The prospect of joining titanium alloys to advanced ceramics and producing components with extraordinary and unique properties can expand the range of potential applications.
Sónia Simões
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Recent Joining Materials Options for Ceramic Matrix Composites

International Journal of Ceramic Engineering & Science
The urgent need to mitigate climate change has driven the exploration of innovative materials and processes to achieve net‐zero carbon emissions. This work investigates the potential of ceramic matrix composites (CMCs) as alternatives to traditional ...
Valentina Casalegno, Monica Ferraris, Milena Salvo, Carla Malinverni   +3 more
doaj   +1 more source