Results 81 to 90 of about 95,004 (291)

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

Investigation on effect of joint clearance on dynamics of four-bar mechanism [PDF]

open access: yes, 2009
As a result of design, manufacturing and assembly processes or a wear effect, clearances are inevitable at the joints of mechanisms. In this study, dynamic response of mechanism having revolute joints with clearance is investigated.
UZMAY, Ibrahim, Erkaya, Selçuk
core   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu   +11 more
wiley   +1 more source

A Study on the strength of the Bolted Joint & Pin Joint with Hole Clearance

open access: yesJournal of The Korean Society for Composite Materials, 2012
With the wide application of fiber-reinforced composite material in aero-structures and mechanical parts, composite joint have become a very important research area because they are often the weakest sites in composite structures. In this paper, the failure strengths of the bolted joint and pin joint which have variable hole clearance were evaluated ...
Kang-Woo Jeong   +2 more
openaire   +2 more sources

3D Revolute Joint with Clearance in Multibody Systems [PDF]

open access: yes, 2017
The aim of this paper is to understand the influence of radial and axial clearance in the revolute joints on the overall performance of a circuit breaker. A circuit breaker mechanism is made of seven links, seven revolute joints with clearance in both radial and axial direction, four unilateral contacts with friction, and it has forty-two degrees of ...
Akhadkar, Narendra   +2 more
openaire   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

Robust Optimization of Planar Constrained Mechanical System with Varying Joint Clearance Size Based on Sensitivity Analysis [PDF]

open access: yes, 2020
This paper is devoted to a general methodological study on sensitivity analysis and robust optimization for a planar crank-slider mechanism in presence of joint clearances and random parameters and investigate the effects of parameter uncertainty on ...
Fang Zhang, Yong Gao, Yuanyuan Li
core   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle   +4 more
wiley   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright   +10 more
wiley   +1 more source

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