Results 71 to 80 of about 1,326,915 (353)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Компьютеризированная система Multi-Joint System MJS 403 Plus в превентивной реабилитации повреждений и заболеваний плечевого сустава. [PDF]

, 2016
У статті розглянуто особливості застосування системи Multi-Joint System MJS 403 Plus для забезпечення технологій превентивної реабілітації пошкоджень і захворювань плечового суглоба.
Demydenko, Maryna, Popadiukha, Yuriy, Демиденко, Марина Олеговна, Демиденко, Марина Олегівна, Попадюха, Юрий Андреевич, Попадюха, Юрій Андрійович   +5 more
core  

The effect of cigarette smoke exposure on the development of inflammation in lungs, gut and joints of TNFΔARE mice [PDF]

, 2015
The inflammatory cytokine TNF-alpha is a central mediator in many immune-mediated diseases, such as Crohn's disease (CD), spondyloarthritis (SpA) and chronic obstructive pulmonary disease (COPD).
A Churg, A I D'Hulst, A I D'Hulst, A Oberholzer, AN Ananthakrishnan, B Chassaing, BR Vuillemenot, C Ott, Claude A. Cuvelier, D Kontoyiannis, D Kontoyiannis, D Laukens, D Laukens, D Poddubnyy, D Poddubnyy, D Raddatz, D Wendling, Debby Laukens, Dirk Elewaut, E Perry, EM Thomson, G Kollias, G Macdonald, Griet Conickx, Guy F. Joos, Guy G. Brusselle, H Roberts, HS Hreggvidsdottir, J Bagaitkar, J Callhoff, J George, J Karczewski, JC Peng, JJ Peschon, K Chang, K Vermaelen, KA Papadakis, Karlijn Debusschere, Ken R. Bracke, KR Bracke, L Allais, L Arcavi, L Klareskog, Liesbeth Allais, LK Lundblad, LL Dupont, M De Vos, M Montbarbon, Martine De Vos, MF Neurath, P Jacques, P Jacques, P Vassalli, PG Persson, R Matsuda, R Vlahos, R Vlahos, Rebecca De Smet, S Mukhopadhyay, S Suissa, S Tangedal, S Verschuere, S Verschuere, Selvakumar Subbian, SK Biswas, Smitha Kumar, Stephanie Verschuere, Tania Maes, W Strober, Y Arnson   +69 more
core   +3 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Meniscal Allograft Transplantation Made Simple: Bridge and Slot Technique

Arthroscopy Techniques, 2017
Over recent years, appreciation for the critical role of the meniscus in joint biomechanics has led to an emphasis on meniscal preservation. Meniscal allograft transplant (MAT) is a promising biological solution for the symptomatic young patient with a ...
Daniel J. Kaplan, M.D., Sergio A. Glait, M.D., William E. Ryan, Jr., M.D., Michael J. Alaia, M.D., Kirk A. Campbell, M.D., Eric J. Strauss, M.D., Laith M. Jazrawi, M.D.   +6 more
doaj   +1 more source

Ultrasonography of the painful hip in childhood [PDF]

, 1999
There are many diseases in childhood that affect the hip joint. Some diseases are systemic in origin and initially may present themselves as hip disorders, such as rheumatoid arthritis.
Robben, S.G.F. (Simon)
core   +2 more sources

Disseminated cutaneous gout: a rare manifestation of a common disease [PDF]

, 2020
Disseminated cutaneous gout is a rare atypical cutaneous manifestation of gout in which widespread dermal and subcutaneous tophi develop at extra-articular body sites.
Adler, Brandon L, Crew, Ashley, DeClerck, Brittney, Guzman, Ruben, Peng, David   +4 more
core  

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Arthroscopic Rotator Cuff Repair: Double-Row Transosseous Equivalent Suture Bridge Technique

Arthroscopy Techniques, 2016
Following a failed course of conservative management, arthroscopic rotator cuff repair (ARCR) has become the gold standard treatment for patients presenting with symptomatic rotator cuff (RC) tears. Traditionally, the single-row repair technique was used.
Mina Abdelshahed, M.D., Siddharth A. Mahure, M.D., M.B.A., Daniel J. Kaplan, B.A., Brent Mollon, M.D., F.R.C.S.C., Joseph D. Zuckerman, M.D., Young W. Kwon, M.D., Ph.D., Andrew S. Rokito, M.D.   +6 more
doaj   +1 more source

Sequential expression of Lgr5 and Col22a1 in developing synovial joints marks the progressive differentiation of progenitor cells to articular chondrocytes [PDF]

, 2014
Poster Presentation - Theme 3: Development & stem cellsHealthy articular cartilage in synovial joints provides a smooth, wear-resistant structure that reduces friction and absorbs impact forces.
Chan, D, Feng, C
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