Results 51 to 60 of about 589,923 (295)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

The Effects of Adding Attachments in Conventional Composite Hybrid Joints on Tensile Strength [PDF]

open access: yes, 2010
Mechanical fasteners are commonly used in today’s composite aircraft adhesive joints. The primary purpose for using mechanical fasteners was to provide redundancy to the adhesive joints because of the uncertainties associated with an adhesive only joint.
Wang, Peng Hao
core  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Design and analysis of DLS steel/composite thick-adhernd adhesive joints

open access: yes, 2009
The paper describes experimental and numerical techniques to study the structural design and behaviourof thick-adherend DLS joints that are based on steel /steel and steel/composites and epoxy adhesives, withfocus on long overlap joints.
Juin, E.   +10 more
core   +1 more source

Corrosion Properties of Various Copper Pipes Joints

open access: yesCommunications, 2014
The paper presents the experimental results of various Cu pipes joint corrosion behavior. Joining of copper pipes used for liquid media transport can be made as demountable and fixed joints.
Tatiana Liptakova   +4 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Using deep networks for knee range of motion monitoring in total knee arthroplasty rehabilitation

open access: yesFrontiers in Bioengineering and Biotechnology
BackgroundKnee range of motion (ROM) is a key indicator of rehabilitation after total knee arthroplasty (TKA). Current tools, such as visual and protractor measurements, are cumbersome, imprecise, and require professional training, limiting their use in ...
Yi-Xiang Zhang   +10 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Glaucocalyxin A delays the progression of OA by inhibiting NF-κB and MAPK signaling pathways

open access: yesJournal of Orthopaedic Surgery and Research
Background Osteoarthritis (OA) is a common degenerative joint condition marked by inflammation and cartilage breakdown. Currently, there is a dearth of treatment medications that can clearly slow the course of OA.
Xin Hong   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy