Results 51 to 60 of about 571,983 (243)

Using deep networks for knee range of motion monitoring in total knee arthroplasty rehabilitation

Frontiers in Bioengineering and Biotechnology
BackgroundKnee range of motion (ROM) is a key indicator of rehabilitation after total knee arthroplasty (TKA). Current tools, such as visual and protractor measurements, are cumbersome, imprecise, and require professional training, limiting their use in ...
Yi-Xiang Zhang, Yi-Xiang Zhang, Qiu-Yu Wang, Tao Yang, Tao Yang, Jia-He Wang, Hao-Tian Yin, Hao-Tian Yin, Lei Wang, Jun Liu, Jun Liu   +10 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Glaucocalyxin A delays the progression of OA by inhibiting NF-κB and MAPK signaling pathways

Journal of Orthopaedic Surgery and Research
Background Osteoarthritis (OA) is a common degenerative joint condition marked by inflammation and cartilage breakdown. Currently, there is a dearth of treatment medications that can clearly slow the course of OA.
Xin Hong, Xuqiang Liu, Bo Li, Shoujie Shi, Kai Xiao, Tiantian Xu, Yaoyang Nie, Min Dai, Meisong Zhu   +8 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Finite-Element Analysis of Shear-off Failure of Keyed Dry Joints in Precast Concrete Segmental Bridges [PDF]

, 2014
This article has been made available through the Brunel Open Access Publishing Fund.The structural behaviour of precast concrete segmental bridges is largely dependent on the behaviour of the joints between segments.
M. Asce, Giulio Alfano, Rabee Shamass, Zhou, X, Shamass, R, Ph. D, Alfano, G, Xiangming Zhou   +7 more
core   +1 more source

Videos in short-video sharing platforms as sources of information on osteoarthritis: cross-sectional content analysis study

Frontiers in Digital Health
BackgroundOsteoarthritis (OA) is a debilitating condition characterized by pain, stiffness, and impaired mobility, significantly affecting patients' quality of life. Health education is crucial in helping individuals understand OA and its management.
Yi-xiang Zhang, Yi-xiang Zhang, Hao-tian Yin, Hao-tian Yin, Ya-xing Liu, Ya-xing Liu, Xin Fu, Jun Liu, Jun Liu, Jun Liu   +9 more
doaj   +1 more source

Spontaneous elbow hemarthrosis identified by point-of-care ultrasound [PDF]

Clinical and Experimental Emergency Medicine, 2017
Traumatic or spontaneous hemarthroses are an important cause of joint effusions, and can complicate innate or acquired coagulopathies. The elbow is an unusual location for a spontaneous hemarthrosis; we describe a previously unreported case of warfarin ...
David C. Mackenzie, Scott McCorvey
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Seismic strengthening of beam-column joints with multidirectional CFRP laminates [PDF]

, 2012
An experimental program was carried out to analyse the potentialities of a technique based on the use of multidirectional CFRP laminates (MDL-CFRP) for the seismic repair and strengthening of reinforced concrete (RC) beam-column joints. This experimental
Costa, A., Barros, Joaquim A. O., Varum, Humberto, Barros, J., Varum, H., Sena-Cruz, José, Coelho, M., Fernandes, P., Sena-Cruz, J., Melo, José, Costa, Aníbal, Coelho, Mário Rui Freitas, Melo, J., Fernandes, Pedro Miguel Gomes   +13 more
core  

Current opinion: where are we in our understanding and treatment of osteoarthritis?

Swiss Medical Weekly, 2016
There has been important recent progress in our understanding of the molecular pathology of osteoarthritis (OA) and how it might be treated. New technologies have been developed and others refined to identify patients for recruitment in clinical trials
Anthony Robin Poole
doaj   +1 more source