Results 61 to 70 of about 3,379,584 (355)

Design and analysis of joints between light composite superstructure and steel hull

open access: yesZhongguo Jianchuan Yanjiu, 2020
[Objectives] Designing effective and reliable composite and steel joints is one of the difficulties faced in the application of composite superstructure in ships.[Methods] Considering the advantages and disadvantages of various joint structures,the π ...
LI Han, GUO Zhanyi
doaj   +1 more source

Pipe joints reinforced in place with fitted aluminum sleeves [PDF]

open access: yes, 1967
Installation of an aluminum sleeve, using specially designed tools, reinforces solder- sealed ferrule joints in installed small-diameter aluminum tubing.
Cortez, I., Jr.   +2 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Using deep networks for knee range of motion monitoring in total knee arthroplasty rehabilitation

open access: yesFrontiers in Bioengineering and Biotechnology
BackgroundKnee range of motion (ROM) is a key indicator of rehabilitation after total knee arthroplasty (TKA). Current tools, such as visual and protractor measurements, are cumbersome, imprecise, and require professional training, limiting their use in ...
Yi-Xiang Zhang   +10 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Glaucocalyxin A delays the progression of OA by inhibiting NF-κB and MAPK signaling pathways

open access: yesJournal of Orthopaedic Surgery and Research
Background Osteoarthritis (OA) is a common degenerative joint condition marked by inflammation and cartilage breakdown. Currently, there is a dearth of treatment medications that can clearly slow the course of OA.
Xin Hong   +8 more
doaj   +1 more source

Videos in short-video sharing platforms as sources of information on osteoarthritis: cross-sectional content analysis study

open access: yesFrontiers in Digital Health
BackgroundOsteoarthritis (OA) is a debilitating condition characterized by pain, stiffness, and impaired mobility, significantly affecting patients' quality of life. Health education is crucial in helping individuals understand OA and its management.
Yi-xiang Zhang   +9 more
doaj   +1 more source

Corrosion Properties of Various Copper Pipes Joints

open access: yesCommunications, 2014
The paper presents the experimental results of various Cu pipes joint corrosion behavior. Joining of copper pipes used for liquid media transport can be made as demountable and fixed joints.
Tatiana Liptakova   +4 more
doaj   +1 more source

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