Results 51 to 60 of about 240,947 (277)

CRISPR/Cas9‐Assisted Microrobots for Fast and Ultrasensitive “On‐The‐Fly” Next‐Generation DNA Detection

open access: yesAdvanced Functional Materials, EarlyView.
This work presents self‐propelled CRISPR/Cas9‐functionalized Au–MRs for rapid, amplification‐free, “on‐the‐fly” DNA detection. By harnessing motion‐assisted signal recovery, the platform achieved the limit of detection in low fM DNA concentrations, enabling detection across a wide dynamic range within only 5 min, which is significantly faster than any ...
Jyoti   +3 more
wiley   +1 more source

What Trends in Chinese Social Media [PDF]

open access: yes, 2011
There has been a tremendous rise in the growth of online social networks all over the world in recent times. While some networks like Twitter and Facebook have been well documented, the popular Chinese microblogging social network Sina Weibo has not been
Asur, Sitaram   +2 more
core   +2 more sources

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

open access: yesAdvanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu   +14 more
wiley   +1 more source

Endothelial Cells Angiogenesis in Sulfated Glycosaminoglycan (GAG) Hydrogels Enhanced by Bioactive Glass‐Released Ions

open access: yesAdvanced Functional Materials, EarlyView.
A mechanically tunable hydrogel composed of gelatin, chondroitin sulfate and laminin promotes angiogenesis in vitro without the supplement of growth factors. Endothelial cells morphogenesis was further enhanced by medium conditioned with bioactive glass 58S‐released ions (Ca and Si), thus offering a promising strategy to vascularize 3D tissue ...
Marco Piazzoni   +13 more
wiley   +1 more source

Cardwell, Judith (FA 979) [PDF]

open access: yes, 2016
Finding aid only for Folklife Archives Project 979. Project titled: “Elephant Jokes.” Includes survey sheets with elephant jokes and the informant’s name collected from Jefferson County, Monroe County, Muhlenburg County, and Warren County, Kentucky ...
Folklife Archives, Manuscripts &
core   +1 more source

In Defense of Comic Pluralism [PDF]

open access: yes, 2017
Jokes are sometimes morally objectionable, and sometimes they are not. What’s the relationship between a joke’s being morally objectionable and its being funny? Philosophers’ answers to this question run the gamut.
Sharadin, Nathaniel
core   +1 more source

Injectable Dual‐Network Hydrogel System for Osteochondral Repair Combining Immunomodulation, Mechanical Adaptability, and Enhanced Tissue Integration

open access: yesAdvanced Functional Materials, EarlyView.
A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui   +10 more
wiley   +1 more source

Satirical Politics and Late-Night Television Ratings [PDF]

open access: yes, 2018
Since the 2016 Presidential election, it has become increasingly difficult to turn on the television or log onto social media without being informed of everything happening at The White House. This includes late-night television.
Johnson, Tanner
core   +1 more source

David Foster Wallace's treatment of therapy after postmodernism [PDF]

open access: yes, 2017
Despite the critical consensus that a major part of David Foster Wallace’s project was to challenge the paradigms of postmodernism, there is an assumption that, when it comes to therapy, Wallace did little more than tell the same postmodern jokes.
Redgate, Jamie
core   +1 more source

Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction

open access: yesAdvanced Functional Materials, EarlyView.
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch   +13 more
wiley   +1 more source

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