Results 91 to 100 of about 185,227,745 (225)

Corrigendum to “New Silver N-Heterocyclic Carbenes Complexes: Synthesis, Molecular Docking Study and Biological Activities Evaluation as cholinesterase inhibitors and antimicrobials” [Journal of Molecular Structure 1238 (2021) 130399]

Journal of Molecular Structure, 2021
Sarra Lasmari, Sofiane Ikhlef, Raouf Boulcina, El Hassen Mokrani, Chawki Bensouici, Nevin Gürbüz, Muhmammed Dündar, Hüseyin Karcı, İlknur Özdemir, Ahmet Koç, Ismail Özdemir, Abdelmadjid Debache   +11 more
openaire   +1 more source

Bioimage management and analysis in Galaxy: Tools, workflows, training, and community practices

Journal of Microscopy, EarlyView.
ABSTRACT Image analysis in the life sciences is constrained by fragmented software ecosystems, heterogeneous data formats, and limited reproducibility. These barriers hinder the reuse of image analysis methods and the sustainability of tools. In this article, we describe how the Galaxy platform enables FAIR (Findable, Accessible, Interoperable, and ...
Leonid Kostrykin, Riccardo Massei, Diana Chiang, Thomas Wollmann, Jean‐Marie Burel, David Lopez Tabernero, Yi Sun, Qi Gao, Maarten W. Paul, Pavankumar Videm, Cameron Watson, Daniel Franco‐Barranco, Anup Kumar, Nadia Goué, Reyhaneh Tavakoli Koopaei, Vladimír Ulman, Khaled Jum'ah, Krzysztof Poterlowicz, Martin Etzrodt, Arrate Muñoz‐Barrutia, Sylvia E. Le Dévédec, Josh Moore, Jeremy Goecks, Bjoern Gruening, Karl Rohr, Beatriz Serrano‐Solano   +25 more
wiley   +1 more source

Selective modulation of NaV channel gating counteracts aberrant hyperexcitability and rescues motor function and survival in a model of spinal muscular atrophy

British Journal of Pharmacology, Volume 183, Issue 23, Page 6824-6846, December 2026.
Background and Purpose Spinal muscular atrophy (SMA) is a motor neuron disease caused by SMN1 gene loss, leading to reduced survival motor neuron (SMN) protein and progressive motor neuron degeneration. Although SMN‐restoring therapies improve outcomes, residual disease burden and non‐curative efficacy underscore the need for complementary treatments ...
Fernanda C. Cardoso, Jessica A. I. Muller, Yougang Zhang, Jean Giacomotto   +3 more
wiley   +1 more source

Natural products in treating diabetic kidney disease: a visualized bibliometric analysis

Frontiers in Pharmacology
BackgroundDiabetic kidney disease (DKD) is one of the most significant complications in diabetic patients, yet current therapeutic options are limited. The advantages of natural products in treating chronic diseases have increasingly garnered attention ...
Tianlong Liu, Tianlong Liu, Xiaolin Li, Yidan Chen, Jinhu Li, Rong Wang, Yi Ding, Minna Liu   +7 more
doaj   +1 more source

Five decades of cancer research in Jordan: A thematic mapping of clinical, translational, and emerging technological trends (1974–2024) [PDF]

International Journal of One Health
Background and Aim: Cancer represents a major public health challenge in Jordan and remains one of the leading causes of morbidity and mortality. Over the past five decades, Jordan has developed a substantial body of cancer-related research spanning ...
Yasser Bustanji, Amani A. Harb, Jalal Taneera, Shereen M. Aleidi, Rula Darwish, Ahmad Y. Abuhelwa, Mahmoud Al-Masri, Islam Hamad, Kamal Al-Rabi, Waseem El-Huneidi, Eman Abu-Gharbieh, Mohammad H. Semreen   +11 more
doaj   +1 more source

F7 Drives Gastric Cancer Metastasis Through Anoikis Resistance and Tumor Microenvironment Remodeling

Advanced Science, Volume 13, Issue 61, 3 November 2026.
ABSTRACT Coagulation factor VII (F7) has been implicated in tumor progression; however, its role in gastric cancer metastasis and immune evasion remains incompletely understood. In this study, we identified F7 as a clinically relevant driver of gastric cancer.
Lei Gao, Qinying Han, Yunpeng Wang, Xuemei Li, Bofang Wang, Baohong Gu, Weidong Li, Lin Xiang, Ying Zhang, Hao Chen   +9 more
wiley   +1 more source

Supramolecular complex formed by DNA oligonucleotide and thiacalix[4]arene. NMR-spectroscopy and molecular docking [PDF]

, 2014
The combination of NMR-spectroscopy and molecular docking was applied to investigate the complexation of thiacalix[4]arene with DNA. We have studied the structure of supramolecular complex formed by palindromic decamer DNA d(GCGTTAACGC)2 and ...
Khairutdinov B., Ermakova E., Zuev Y., Stoikov I., Sitnitsky A.   +4 more
core  

Selective AUTAC‐mediated ATP7B degradation unlocks cuproptosis vulnerability in pancreatic ductal adenocarcinoma

Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.
ATP7B is aberrantly upregulated in PDAC cells, contributing to the maintenance of copper homeostasis. We designed ATAUTAC, a targeted autophagy‐dependent degradation molecule that selectively eliminates ATP7B. By disrupting copper balance, ATAUTAC sensitizes PDAC cells to cuproptosis, thereby amplifying copper‐induced metabolic stress and effectively ...
Zihan Zhang, Min Li, Jiale Feng, Jian‐Ang Li, Lei Zhang   +4 more
wiley   +1 more source

Mapping the research landscape of minor cannabinoids: a bibliometric analysis of research trends and hotspots

Journal of Cannabis Research
Background Minor cannabinoids, including cannabigerol (CBG), cannabinol (CBN), and cannabichromene (CBC), are gaining scientific attention for their distinct therapeutic potential beyond THC and CBD.
Hanane Abbou, Lahcen Belyamani, Rachid Eljaoudi   +2 more
doaj   +1 more source

Acknowledgement to Reviewers of International Journal of Molecular Sciences in 2016

, 2017
The editors of International Journal of Molecular Sciences would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2016.[...
International Journal of Molecular Sciences Editorial Office
core   +1 more source