Results 101 to 110 of about 185,227,745 (225)

Comprehensive genomic profiling of mucosal melanoma reveals novel fusion transcripts and dysregulation of cell‐cycle, MAPK, and PI3K pathways

open access: yesThe Journal of Pathology, Volume 270, Issue 3, Page 380-395, November 2026.
Abstract Mucosal melanomas (MMs) are rare, aggressive cancers with poor outcomes and limited response to standard therapies. A significant knowledge gap exists regarding their genomic landscape and corresponding druggable targets. This study explores this issue through a multi‐omic analysis, including whole exome‐, RNA‐, and targeted sequencing, of ...
Matilde Monti   +21 more
wiley   +1 more source

Effectiveness of herbal medicine for liver cancer treatment as revealed by a bibliometric and visualization analysis

open access: yesFrontiers in Oncology
BackgroundLiver cancer is highly prevalent worldwide. However, current medical treatments remain insufficient. Although herbal medicine has a long history and extensive expertise in treating liver cancer, the literature in this field has not been ...
Yusha Shi   +6 more
doaj   +1 more source

Enhancing protein-protein docking by new approaches to protein flexibility and scoring of docking hypotheses [PDF]

open access: yes, 2004
Zöllner FG. Enhancing protein-protein docking by new approaches to protein flexibility and scoring of docking hypotheses. Bielefeld (Germany): Bielefeld University; 2004.Für das Verständnis von biologischen Funktionen können Proteindockingverfahren ...
Frank G. Zöllner   +1 more
core  

Acknowledgement to Reviewers of International Journal of Molecular Sciences in 2015

open access: yes, 2016
The editors of International Journal of Molecular Sciences would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015.
International Journal of Molecular Sciences Editorial Office
core   +1 more source

Identification of Potential Biomarkers for Ulcerative Colitis and Analysis of Immune Cell Infiltration: A Study Based on Data‐Independent Acquisition Proteomics and the GEO Public Database

open access: yesPROTEOMICS – Clinical Applications, Volume 20, Issue 6, November 2026.
ABSTRACT Background Ulcerative colitis (UC) is a challenging inflammatory bowel disease characterized by chronic inflammation of the colon's mucosal layer. Despite advances in medical research, UC lacks definitive diagnostic tests and targeted treatments.
Shuai Wang, Hualiang Deng, Dajuan Sun
wiley   +1 more source

QCSPScore: a new scoring function for driving protein-ligand docking with quantitative chemical shifts perturbations [PDF]

open access: yes, 2010
Through the use of information about the biological target structure, the optimization of potential drugs can be improved. In this work I have developed a procedure that uses the quantitative change in the chemical perturbations (CSP) in the protein from
González Ruiz, Domingo
core  

Acknowledgement to Reviewers of the International Journal of Molecular Sciences in 2017

open access: yes, 2018
Peer review is an essential part in the publication process, ensuring that the International Journal of Molecular Sciences maintains high quality standards for its published papers [...
International Journal of Molecular Sciences Editorial Office
core   +1 more source

Crystal structure of tyrosine‐tRNA synthetase from Helicobacter pylori G27

open access: yesActa Crystallographica Section F, Volume 82, Issue 11, Page 369-375, November 2026.
The production, crystallization and 2.2 Å resolution structure of H. pylori tyrosine‐tRNA synthetase are reported.Helicobacter pylori, a major cause of gastric ulcers and cancers, infects nearly half of the world's population. The crystal structure of a potential H.
David Igbalajobi   +13 more
wiley   +1 more source

Visual Analysis of Traditional Chinese Medicine Used in Treating Lung Cancer Based on the Web of Science Database

open access: yesWorld Journal of Traditional Chinese Medicine
Objective: We undertook a knowledge map-based visual analysis of the literature concerning the use of Traditional Chinese Medicine (TCM) for treating lung cancer.
Fang-Fang Qin   +4 more
doaj   +1 more source

Supramolecular complex formed by DNA oligonucleotide and thiacalix[4]arene. NMR-spectroscopy and molecular docking

open access: yes, 2020
The combination of NMR-spectroscopy and molecular docking was applied to investigate the complexation of thiacalix[4]arene with DNA. We have studied the structure of supramolecular complex formed by palindromic decamer DNA d(GCGTTAACGC)2 and ...
Khairutdinov B.   +4 more
core  

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