Results 101 to 110 of about 185,227,745 (225)
Abstract Mucosal melanomas (MMs) are rare, aggressive cancers with poor outcomes and limited response to standard therapies. A significant knowledge gap exists regarding their genomic landscape and corresponding druggable targets. This study explores this issue through a multi‐omic analysis, including whole exome‐, RNA‐, and targeted sequencing, of ...
Matilde Monti +21 more
wiley +1 more source
BackgroundLiver cancer is highly prevalent worldwide. However, current medical treatments remain insufficient. Although herbal medicine has a long history and extensive expertise in treating liver cancer, the literature in this field has not been ...
Yusha Shi +6 more
doaj +1 more source
Enhancing protein-protein docking by new approaches to protein flexibility and scoring of docking hypotheses [PDF]
Zöllner FG. Enhancing protein-protein docking by new approaches to protein flexibility and scoring of docking hypotheses. Bielefeld (Germany): Bielefeld University; 2004.Für das Verständnis von biologischen Funktionen können Proteindockingverfahren ...
Frank G. Zöllner +1 more
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Acknowledgement to Reviewers of International Journal of Molecular Sciences in 2015
The editors of International Journal of Molecular Sciences would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015.
International Journal of Molecular Sciences Editorial Office
core +1 more source
ABSTRACT Background Ulcerative colitis (UC) is a challenging inflammatory bowel disease characterized by chronic inflammation of the colon's mucosal layer. Despite advances in medical research, UC lacks definitive diagnostic tests and targeted treatments.
Shuai Wang, Hualiang Deng, Dajuan Sun
wiley +1 more source
QCSPScore: a new scoring function for driving protein-ligand docking with quantitative chemical shifts perturbations [PDF]
Through the use of information about the biological target structure, the optimization of potential drugs can be improved. In this work I have developed a procedure that uses the quantitative change in the chemical perturbations (CSP) in the protein from
González Ruiz, Domingo
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Acknowledgement to Reviewers of the International Journal of Molecular Sciences in 2017
Peer review is an essential part in the publication process, ensuring that the International Journal of Molecular Sciences maintains high quality standards for its published papers [...
International Journal of Molecular Sciences Editorial Office
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Crystal structure of tyrosine‐tRNA synthetase from Helicobacter pylori G27
The production, crystallization and 2.2 Å resolution structure of H. pylori tyrosine‐tRNA synthetase are reported.Helicobacter pylori, a major cause of gastric ulcers and cancers, infects nearly half of the world's population. The crystal structure of a potential H.
David Igbalajobi +13 more
wiley +1 more source
Objective: We undertook a knowledge map-based visual analysis of the literature concerning the use of Traditional Chinese Medicine (TCM) for treating lung cancer.
Fang-Fang Qin +4 more
doaj +1 more source
The combination of NMR-spectroscopy and molecular docking was applied to investigate the complexation of thiacalix[4]arene with DNA. We have studied the structure of supramolecular complex formed by palindromic decamer DNA d(GCGTTAACGC)2 and ...
Khairutdinov B. +4 more
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