Results 91 to 100 of about 654 (107)

Jumbo phages

Here we collected 59,652,008 putative viral genomes spanning seven different habitats by using 38 public metagenome datasets, an integrated public viral genome database (IGNR), and a pig gut viral genome database (PGV). A total of 10,754 megaphage genomes were obtained with genome sizes from 200 to 831 kb.
Wei, Chao, Huang, Lusheng
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A novel jumbo Tenacibaculum maritimum lytic phage with head-fiber-like appendages

Archives of Virology, 2019
A novel jumbo bacteriophage (myovirus) is described. The lytic phage of Tenacibaculum maritimum, which is the etiological agent of tenacibaculosis in a variety of farmed marine fish worldwide, was plaque-isolated from seawater around a fish aquaculture field in Japan. The phage had an isometric head 110-120 nm in diameter, from which several 50- to 100-
Yasuhiko Kawato, Indah Istiqomah, Alkhateib Y. Gaafar, Makoto Hanaoka, Katsuya Ishimaru, Motoshige Yasuike, Issei Nishiki, Yoji Nakamura, Atushi Fujiwara, Toshihiro Nakai   +9 more
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A cytoskeletal vortex drives phage nucleus rotation during jumbo phage replication in E. coli.

2022
Nucleus-forming jumbo phages establish an intricate subcellular organization, enclosing phage genomes within a proteinaceous shell called the phage nucleus. During infection in Pseudomonas, some jumbo phages assemble a bipolar spindle of tubulin-like PhuZ filaments that positions the phage nucleus at midcell and drives its intracellular rotation.
Birkholz, Erica A, Laughlin, Thomas G, Armbruster, Emily, Suslov, Sergey, Lee, Jina, Wittmann, Johannes, Corbett, Kevin D, Villa, Elizabeth, Pogliano, Joe   +8 more
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Conserved jumbo phage factors required for protein import into a phage nucleus

AbstractBacteriophages use diverse mechanisms to evade anti-phage defenses systems. ΦKZ-like jumbo phages assemble a proteinaceous nucleus-like compartment that excludes antagonistic host nucleases, while internalizing DNA replication and transcription machinery1,2,3,4.
Claire Kokontis, Timothy A Klein, Sukrit Silas, Joseph Bondy-Denomy   +3 more
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Jumbo Phages

2021
Isaac T. Younker, Carol Duffy
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Isolation and Characterization of Salmonella Jumbo-Phage pSal-SNUABM-04

Viruses, 2021
Sang Guen Kim, Hyoun Joong Kim, Sib Sankar Giri   +2 more
exaly  

Investigating the early stages of infection of nucleus-forming jumbo phage

Biophysical Journal, 2023
Zaida K. Rodriguez, Thomas G. Laughlin, Arica VanderWal, Ann Aindow, Alma Razavilar, Amy M. Prichard, Jina Lee, Emily Armbruster, Joe Pogliano, Elizabeth Villa   +9 more
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Hairy jumbo phages of Enterobacteriaceae

2017
Buttimer, Colin, Born, Yannick, Hendrix, Hanne, Oliveria, Hugo, Mcauliffe, Olivia, Neve, Horst, R Paul Ross, Hill, Colin, Noben, Jean-Paul, O'mahony, Jim, Loessner, Martin J, Fieseler, Lars, Lavigne, Rob, Coffey, Aidan   +13 more
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Defining the constituents and functions of a lipid-based jumbo phage compartment

ABSTRACTViruses are vulnerable to cellular defenses at the start of the infection when a single copy genome has not yet initiatedde novoviral protein synthesis. A family of jumbo phages related to phage ΦKZ, which infectsPseudomonas aeruginosa,uses a protein-based phage nucleus to protect the DNA during middle and late stages of infection, but how it ...
Deepto Mozumdar, Andrea Fossati, Erica Stevenson, Jingwen Guan, Eliza Nieweglowska, Sanjana Rao, David Agard, Danielle L. Swaney, Joseph Bondy-Denomy   +8 more
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Architecture and self-assembly of the jumbo bacteriophage nuclear shell

Nature, 2022
Thomas G Laughlin, Christian G Seitz, J Andrew Mccammon   +2 more
exaly