Characterization of a novel genus of jumbo phages and their application in wastewater treatment [PDF]
IScience, 2023 Summary: Phages widely exist in numerous environments from wastewater to deep ocean, representing a huge virus diversity, yet remain poorly characterized.
Congzhao Zhou, Wenchen Song
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The Phage Nucleus and PhuZ Spindle: Defining Features of the Subcellular Organization and Speciation of Nucleus-Forming Jumbo Phages [PDF]
Frontiers in Microbiology, 2021 Bacteriophages and their bacterial hosts are ancient organisms that have been co-evolving for billions of years. Some jumbo phages, those with a genome size larger than 200 kilobases, have recently been discovered to establish complex subcellular ...
Vorrapon Chaikeeratisak +2 more
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Jumbo Phages: A Comparative Genomic Overview of Core Functions and Adaptions for Biological Conflicts [PDF]
Viruses, 2021 Jumbo phages have attracted much attention by virtue of their extraordinary genome size and unusual aspects of biology. By performing a comparative genomics analysis of 224 jumbo phages, we suggest an objective inclusion criterion based on genome size ...
Lakshminarayan M Iyer +2 more
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Exploring pangenomic diversity and CRISPR-Cas evasion potential in jumbo phages: a comparative genomics study [PDF]
Microbiology SpectrumJumbo phages are characterized by their remarkably large-sized genome and unique life cycles. Jumbo phages belonging to Chimalliviridae family protect the replicating phage DNA from host immune systems like CRISPR-Cas and restriction-modification system ...
Sharayu Magar +2 more
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Gastrointestinal jumbo phages possess independent synthesis and utilization systems of NAD+ [PDF]
MicrobiomeBackground Jumbo phages, phages with genomes > 200 kbp, contain some unique genes for successful reproduction in their bacterial hosts. Due to complex and massive genomes analogous to those of small-celled bacteria, how jumbo phages complete their life ...
Kaiping Liu, Shengwei Hu, Li Cunyuan
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Capsid structure of bacteriophage ΦKZ provides insights into assembly and stabilization of jumbo phages [PDF]
Nature CommunicationsJumbo phages are a group of tailed bacteriophages with large genomes and capsids. As a prototype of jumbo phage, ΦKZ infects Pseudomonas aeruginosa, a multi-drug-resistant (MDR) opportunistic pathogen leading to acute or chronic infection in ...
Qianglin Fang, Lei Sun, Zhenguo Chen
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Replications of Two Closely Related Groups of Jumbo Phages Show Different Level of Dependence on Host-encoded RNA Polymerase [PDF]
Frontiers in Microbiology, 2017 Ralstonia solanacearum phages ΦRP12 and ΦRP31 are jumbo phages isolated in Thailand. Here we show that they exhibit similar virion morphology, genome organization and host range.
Genki Yoshikawa +2 more
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Comprehensive genome analysis uncovers the diversity of jumbo phages in the pig gut microbiome [PDF]
Frontiers in Veterinary ScienceGut microbiome research has historically focused on bacterial communities. In contrast, the roles of viruses, especially jumbo phages, remain poorly understood.
Chao Wei, Zhe Chen
doaj +2 more sources
Large-scale genomic analysis of jumbo phages: coevolution, genome architecture, and host interaction mechanisms [PDF]
Animal MicrobiomeBackground Jumbo phages are phages with comparatively large genome sizes. Jumbo phages have been identified in various microbial communities. However, their diversity, genome structure, potential function, and their interactions with hosts and other ...
Chao Wei +4 more
doaj +2 more sources
The biology of jumbo phages [PDF]
Nature CommunicationsJumbo bacteriophages are bacterial viruses with double-stranded DNA genomes exceeding 200 kb. These viral giants feature exceptionally large virions, expansive genetic repertoires, and in some cases, remarkable eukaryotic-like traits.
Sam P. B. van Beljouw, Li Yuping
doaj +2 more sources