Characterization and genomic analysis of Sharanji: a jumbo bacteriophage of Escherichia coli [PDF]
Virology JournalBackground Bacteriophages are the most genetically diverse biological entities in nature. Our current understanding of phage biology primarily stems from studies on a limited number of model bacteriophages.
Sharayu Magar +6 more
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The Biology of Nucleus-Forming Jumbo Phages. [PDF]
Annu Rev GenetNucleus-forming jumbo bacteriophages display a surprisingly intricate replication cycle inside of bacterial host cells, challenging the long-standing paradigm of prokaryotic simplicity.
Birkholz EA, Armbruster EG, Pogliano J.
europepmc +4 more sources
The complex developmental mechanisms of nucleus-forming jumbo phages. [PDF]
Curr Opin MicrobiolBacteriophages related to the jumbo phage ΦKZ (Family: Chimalliviridae) exhibit a complex developmental cycle. During infection, two large macromolecular compartments are assembled that surround and protect the bacteriophage genome.
Mozumdar D, A Agard D, Bondy-Denomy J.
europepmc +5 more sources
Phages Preying on Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis: Past, Present and Future [PDF]
Viruses, 2014 Many bacteriophages (phages) have been widely studied due to their major role in virulence evolution of bacterial pathogens. However, less attention has been paid to phages preying on bacteria from the Bacillus cereus group and their contribution to the ...
Annika Gillis +2 more
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Interactions between Jumbo Phage SA1 and Staphylococcus: A Global Transcriptomic Analysis
Microorganisms, 2022 Staphylococcus aureus (S. aureus) is an important zoonotic pathogen that poses a serious health concern to humans and cattle worldwide. Although it has been proven that lytic phages may successfully kill S.
Bingyan Zhang +4 more
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Unexplored diversity and molecular genetic signatures of chimallin and phuz encoding phages [PDF]
BMC GenomicsNucleus-forming phages are a class of jumbo phages with the capacity to form a protein nuclear shell during infection within a bacterial host. This protein nuclear shell protects the replication of the phage genome by excluding host defense factors ...
Shize Sun +13 more
doaj +3 more sources
In-Gel Isolation and Characterization of Large (and Other) Phages
Viruses, 2020 We review some aspects of the rapid isolation of, screening for and characterization of jumbo phages, i.e., phages that have dsDNA genomes longer than 200 Kb.
Philip Serwer, Elena T. Wright
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Therapeutic application of a jumbo bacteriophage against metallo-β-lactamase producing Pseudomonas aeruginosa clinical isolates [PDF]
Journal of Biomedical ScienceBackground Therapeutic options against metallo-β-lactamase producing P. aeruginosa (MBL-PA) are limited due to multi-drug resistance. A jumbo phage isolated from wastewater in Greece was characterized microbiologically and genetically and evaluated for ...
Paschalis Paranos +9 more
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Characterization of Novel Erwinia amylovora Jumbo Bacteriophages from Eneladusvirus Genus
Viruses, 2020 Jumbo phages, which have a genome size of more than 200 kb, have recently been reported for the first time. However, limited information is available regarding their characteristics because few jumbo phages have been isolated.
Sang Guen Kim +8 more
doaj +2 more sources
AntibioticsBacterial spot is a serious disease caused by several species of Xanthomonas affecting pepper and tomato production worldwide. Since the strategies employed for disease management have been inefficient and pose a threat for environmental and human health,
Claudia Villicaña +5 more
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