Results 11 to 20 of about 112,531 (165)

Characterization of two related Erwinia myoviruses that are distant relatives of the PhiKZ-like Jumbo phages. [PDF]

PLoS ONE, 2018
Bacteriophages are a major force in the evolution of bacteria due to their sheer abundance as well as their ability to infect and kill their hosts and to transfer genetic material.
Daniel K Arens, T Scott Brady, John L Carter, Jenny A Pape, David M Robinson, Kerri A Russell, Lyndsay A Staley, Jason M Stettler, Olivia B Tateoka, Michelle H Townsend, Kiara V Whitley, Trevor M Wienclaw, Taryn L Williamson, Steven M Johnson, Julianne H Grose   +14 more
doaj   +4 more sources

Genomic Characterization of Jumbo Salmonella Phages That Effectively Target United Kingdom Pig-Associated Salmonella Serotypes

Frontiers in Microbiology, 2019
A common cause of human food poisoning is through ingestion of pork products contaminated with Salmonella spp. Worryingly multi-drug resistant (MDR) Salmonella strains have been isolated from pigs, which motivates the need for alternative antimicrobials.
Anisha M Thanki, Andrew D Millard, Martha R J Clokie   +2 more
exaly   +6 more sources

Characterization of a novel Jumbo phage JP4 with potential to control pathogenic Escherichia coli [PDF]

Virology Journal
Background Amidst rising antimicrobial resistance, bacteriophage (phage) therapy has re-emerged as a pivotal weapon against multidrug-resistant pathogens. Jumbo phages, distinguished by large genomes, show particular therapeutic promise.
Kexin Zhang, Xuemei Wei, He Liu, Bo He, Rui Zhao, Jing Zhou, Jun Deng, Fan Xie, Xu Xiong, Gang Li, Yan Zhao, Jing Wang, Zhenhui Song, Shuguang Lu   +13 more
doaj   +5 more sources

fENko-Kae01 is a flagellum-specific jumbo phage infecting Klebsiella aerogenes

BMC Microbiology
Background Klebsiella aerogenes is an opportunistic pathogen that causes a wide variety of infections. Due to the rising problem of antibiotic resistance, novel antibiotics and strategies to combat bacterial infections are needed.
Kira Ranta, Mikael Skurnik, Saija Kiljunen   +2 more
doaj   +6 more sources

Multisubunit RNA Polymerases of Jumbo Bacteriophages

Viruses, 2020
Prokaryotic viruses with DNA genome longer than 200 kb are collectively referred to as “jumbo phages”. Some representatives of this phylogenetically diverse group encode two DNA-dependent RNA polymerases (RNAPs)—a virion RNAP and a non-virion RNAP.
Maria L Sokolova, Konstantin Severinov
exaly   +4 more sources

Pseudomonas Phage PaBG—A Jumbo Member of an Old Parasite Family [PDF]

Viruses, 2020
Bacteriophage PaBG is a jumbo Myoviridae phage isolated from water of Lake Baikal. This phage has limited diffusion ability and thermal stability and infects a narrow range of Pseudomonas aeruginosa strains.
Peter Evseev, Nina Sykilinda, Anna Gorshkova, Lidia Kurochkina, Rustam Ziganshin, Valentin Drucker, Konstantin Miroshnikov   +6 more
doaj   +4 more sources

Jumbo phages are active against extensively drug-resistant eyedrop-associated Pseudomonas aeruginosa infections. [PDF]

Antimicrob Agents Chemother, 2023
Antibiotic-resistant bacteria present an emerging challenge to human health. Their prevalence has been increasing across the globe due in part to the liberal use of antibiotics that has pressured them to develop resistance.
Cobián Güemes AG, Ghatbale P, Blanc AN, Morgan CJ, Garcia A, Leonard J, Huang L, Kovalick G, Proost M, Chiu M, Kuo P, Oh J, Karthikeyan S, Knight R, Pogliano J, Schooley RT, Pride DT.   +16 more
europepmc   +3 more sources

Isolation and Characterization of Salmonella Jumbo-Phage pSal-SNUABM-04 [PDF]

Viruses, 2020
The increasing emergence of antimicrobial resistance has become a global issue. Therefore, many researchers have attempted to develop alternative antibiotics. One promising alternative is bacteriophage.
Jun Kwon, Sang Guen Kim, Hyoun Joong Kim, Sib Sankar Giri, Sang Wha Kim, Sung Bin Lee, Se Chang Park   +6 more
doaj   +4 more sources

Structural atlas of the intact jumbo phage phiKZ [PDF]

Nature Communications
Jumbo phage phiKZ, a key model for studying phage nucleus formation and bacterial defense mechanisms, possesses a highly complex tail machine that is essential for infection.
Hao Xiao, Zeng Peng, Junquan Zhou, Yuan Chen, Yuning Peng, Yixiong Tang, Tao Li, Wenyuan Chen, Sheng-You Huang, Lingpeng Cheng, Hongrong Liu   +10 more
doaj   +3 more sources

vB_PaeM_MIJ3, a Novel Jumbo Phage Infecting Pseudomonas aeruginosa, Possesses Unusual Genomic Features

Frontiers in Microbiology, 2019
Phages are the most abundant biological entity on Earth. There are many variants in phage virion sizes, morphology, and genome sizes. Large virion sized phages, with genome sizes greater than 200 kbp have been identified and termed as Jumbo phages. These
Mohammed İmam, Andrew D Millard, Martha R J Clokie   +2 more
exaly   +4 more sources