Results 41 to 50 of about 112,531 (165)

Proteomic analysis of a novel Bacillus Jumbo phage revealing glycoside hydrolase as structural component

Frontiers in Microbiology, 2016
Tailed phages with genomes of larger than 200 kbp are classified as Jumbo phages and exhibited extremely high uncharted diversity. The genomic annotation of Jumbo phage is often disappointing because most of the predicted proteins, including structural ...
Yihui eYuan, Meiying eGao
doaj   +2 more sources

Next-generation bacteriophage therapeutic systems: CRISPR-based engineering, near-infrared bioimaging, and precision strategies for treating multidrug-resistant and extensively drug-resistant bacterial infections [PDF]

Frontiers in Microbiology
The rapid rise of multidrug-resistant and extensively drug-resistant bacterial infections has renewed interest in bacteriophages as adaptable, targeted antimicrobials.
Zahra Zahid Piracha, Umar Saeed, Umar Saeed   +2 more
doaj   +2 more sources

A flagella-dependent Burkholderia jumbo phage controls rice seedling rot and steers Burkholderia glumae toward reduced virulence in rice seedlings

mBio
Bacteriophages (phages) are being investigated as potential biocontrol agents for the suppression of bacterial diseases in cultivated crops. Jumbo bacteriophages, which possess genomic DNA larger than 200 kbp, generally have a broader host range than ...
Brittany S. I. Supina, Jaclyn G. McCutcheon, Sydney R. Peskett, Paul Stothard, Jonathan J. Dennis   +4 more
doaj   +2 more sources

Systematic bacteriophage selection for the lysis of multiple Pseudomonas aeruginosa strains [PDF]

Frontiers in Cellular and Infection Microbiology
Pseudomonas aeruginosa is an opportunistic pathogen causing severe infections of the lung, burn wounds and eyes. Due to its intrinsic high antibiotic resistance the bacterium is difficult to eradicate.
Finja Rieper, Finja Rieper, Johannes Wittmann, Boyke Bunk, Cathrin Spröer, Melanie Häfner, Christian Willy, Mathias Müsken, Holger Ziehr, Imke H.E. Korf, Dieter Jahn, Dieter Jahn   +11 more
doaj   +2 more sources

Viral whole-genome sequences of <i>Pseudomonas</i> jumbo phages, ΦNK1 and ΦBrmt, from sewage water in Japan. [PDF]

Microbiol Resour Announc
Jumbo phages have potentials for uncovering phage diversity. Here, we report the complete genome sequences of two Pseudomonas jumbo phages, ΦNK1 and ΦBrmt, isolated from waste water in Japan.
Fujiki J, Nakamura T, Ichikawa N, Tamamura K, Yamamoto H, Sakata Y, Nakamura K, Iwano H.   +7 more
europepmc   +2 more sources

Complete genome sequences of two novel Ralstonia jumbo phages isolated from leaf litter compost. [PDF]

Arch Virol
Two Ralstonia phages, FLC1-1B and FLC4-3B, were isolated from leaf litter compost, using Ralstonia pseudosolanacearum, which is a causal agent of bacterial wilt disease, as a host.
Sasaki R, Miyashita S, Takahashi H.
europepmc   +2 more sources

Integrative omics analysis of Pseudomonas aeruginosa virus PA5oct highlights the molecular complexity of jumbo phages. [PDF]

Environ Microbiol, 2020
Pseudomonas virus vB_PaeM_PA5oct is proposed as a model jumbo bacteriophage to investigate phage-bacteria interactions and is a candidate for phage therapy applications.
Lood C, Danis-Wlodarczyk K, Blasdel BG, Jang HB, Vandenheuvel D, Briers Y, Noben JP, van Noort V, Drulis-Kawa Z, Lavigne R.   +9 more
europepmc   +2 more sources

Phage satellites break into the jumbo era. [PDF]

Proc Natl Acad Sci U S A
Penadés JR.
europepmc   +3 more sources

Isolation and characterization of fMGyn-Pae01, a phiKZ-like jumbo phage infecting Pseudomonas aeruginosa

Virology Journal
Background Pseudomonas aeruginosa is an opportunistic pathogen that causes a wide variety of infections, and belongs to the group of ESKAPE pathogens that are the leading cause of healthcare-associated infections and have high level of antibiotic ...
Kira Ranta, Mikael Skurnik, Saija Kiljunen   +2 more
doaj   +2 more sources

Animal-associated jumbo phages as widespread and active modulators of gut microbiome ecology and metabolism. [PDF]

Sci Adv
Huge phages are widespread in the biosphere, yet their prevalence and ecology in the human gut remain poorly characterized. Here, we report Jug (jumbo gut) phages with genomes of 360 to 402 kilobase pairs that comprise ~1.1% of the reads in human gut ...
Chen L, Camargo AP, Qin Y, Koonin EV, Wang H, Zou Y, Duan Y, Li H.   +7 more
europepmc   +2 more sources