Results 91 to 100 of about 871 (146)
The development of new antimicrobial agents is critically needed due to the alarming increase in antibiotic resistance in bacterial pathogens. Phages have been widely considered as effective alternatives to antibiotics.
Qian Wang (32718) +6 more
core +1 more source
In normal PINK1/Parkin‐mediated mitophagy, unlike OPTN (the mitophagy receptor that mediates ATG8‐labeled autophagosome recruitment onto ubiquitinated mitochondria), p62 mediates the clustering of ubiquitinated mitochondria to form the “grape‐like” aggregates with ubiquitin.
Shan Sun +14 more
wiley +1 more source
The emergence of phage-resistant mutants is a key aspect of lytic phages-bacteria interaction and the main driver for the co-evolution between both organisms.
Michal Arabski (742690) +10 more
core +1 more source
DNA Origami and Its Applications in Synthetic Biology
This review provides a comprehensive summary of recent advancements in DNA origami for synthetic biology, emphasizing two key areas: the precise construction and dynamic regulation of extracellular‐to‐intracellular, and the synergistic integration with cell‐free systems.
Yaning Fang +4 more
wiley +1 more source
Mapping protein–protein interactions by mass spectrometry
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu +4 more
wiley +1 more source
Phage nucleus counts and distance measurements.
The emergence of antibiotic resistance in bacteria has led to the investigation of alternative treatments, such as phage therapy. In this study, we examined the interactions between the nucleus-forming jumbo phage ФKZ and antibiotic treatment against ...
Eray Enustun (11984908) +4 more
core +1 more source
Bacteriophages are viruses capable of recognizing with high specificity, propagating inside of, and destroying their bacterial hosts. The phage lytic life cycle makes phages attractive as tools to selectively kill pathogenic bacteria with minimal impact ...
Steven Gayder +4 more
doaj +1 more source
Characterisation of a Novel Jumbo Lytic Aeromonas dhakensis Bacteriophage P19 and Its Endolysin
A jumbo, lytic myovirus phage P19 against multidrug‐resistant (MDR) Aeromonas dhakensis was isolated from river water. P19 demonstrated robust lytic activity, high thermal and pH stability (pH 6–10, up to 60°C), and no genes associated with lysogeny, virulence or antimicrobial resistance. ORF_358 of P19 encodes for T4‐type lysozyme.
Farhat Ansari, Vandan Nagar
wiley +1 more source
Structure, Function, and Assembly of the Jumbo Bacteriophage Nucleus [PDF]
The ΦKZ-like family jumbo bacteriophage ΦPA3 infects the pathogenic bacterium Pseudomonas aeruginosa. Upon infection, the bacteriophage forms a dynamic, bipolar spindle within the host using a divergent tubulin family protein known as phage tubulin/FtsZ ...
Nieweglowska, Eliza Sara
core
Capsid Structure and DNA Packing in Jumbo Bacteriophages [PDF]
Jumbo phages, the phages with genome length larger than 200 Kbp, are extreme examples of how the capsid and genome coordinate in evolution. To learn the mechanism of capsid size change during evolutionary time, the capsid and DNA of several jumbo phages ...
Hua, Jianfei
core

