Results 21 to 30 of about 654 (107)

Comprehensive genome analysis uncovers the diversity of jumbo phages in the pig gut microbiome [PDF]

Frontiers in Veterinary Science
Gut microbiome research has historically focused on bacterial communities. In contrast, the roles of viruses, especially jumbo phages, remain poorly understood.
Chao Wei, Zhe Chen
doaj   +2 more sources

Isolation and characterization of fMGyn-Pae01, a phiKZ-like jumbo phage infecting Pseudomonas aeruginosa [PDF]

Virology Journal
Background Pseudomonas aeruginosa is an opportunistic pathogen that causes a wide variety of infections, and belongs to the group of ESKAPE pathogens that are the leading cause of healthcare-associated infections and have high level of antibiotic ...
Kira Ranta, Mikael Skurnik, Saija Kiljunen   +2 more
doaj   +2 more sources

Isolation, Characterization, and Evaluation of a Lytic Jumbo Phage Z90 Against Aeromonas hydrophila in American Eels (Anguilla rostrata) [PDF]

Antibiotics
Background: Aeromonas hydrophila is a common bacterial pathogen that causes hemorrhagic septicaemia in several farmed aquaculture species. Phage therapy is considered a promising and feasible alternative to antibiotic treatment.
Miaosen Zhang, Xuejin Feng, Jianxin Wang, Wu Qu, Min Jin   +4 more
doaj   +2 more sources

A flagella-dependent Burkholderia jumbo phage controls rice seedling rot and steers Burkholderia glumae toward reduced virulence in rice seedlings [PDF]

mBio
Bacteriophages (phages) are being investigated as potential biocontrol agents for the suppression of bacterial diseases in cultivated crops. Jumbo bacteriophages, which possess genomic DNA larger than 200 kbp, generally have a broader host range than ...
Brittany S. I. Supina, Jaclyn G. McCutcheon, Sydney R. Peskett, Paul Stothard, Jonathan J. Dennis   +4 more
doaj   +2 more sources

Gastrointestinal jumbo phages possess independent synthesis and utilization systems of NAD+

Microbiome
Background Jumbo phages, phages with genomes > 200 kbp, contain some unique genes for successful reproduction in their bacterial hosts. Due to complex and massive genomes analogous to those of small-celled bacteria, how jumbo phages complete their life ...
Cunyuan Li, Kaiping Liu, Chengxiang Gu, Ming Li, Ping Zhou, Linxing Chen, Shize Sun, Xiaoyue Li, Limin Wang, Wei Ni, Meng Li, Shengwei Hu   +11 more
doaj   +4 more sources

Isolation and Characterization of a Novel Jumbo Phage HPP-Temi Infecting Pseudomonas aeruginosa Pa9 and Increasing Host Sensitivity to Ciprofloxacin [PDF]

Antibiotics
Pseudomonas aeruginosa is a bacteria responsible for many hospital-acquired infections. Phages are promising alternatives for treating P. aeruginosa infections, which are often intrinsically resistant. The combination of phage and antibiotics in clearing
Olufunke Olufunmilola Olorundare, Nikita Zrelovs, Dennis Kabantiyok, Karina Svanberga, Juris Jansons, Andris Kazaks, Godwin Ojonugwa Agada, Chibuzor Gerald Agu, Oluwatoyin Ruth Morenikeji, Ogundeji Alice Oluwapelumi, Thomas Dung, Shedrach Benjamin Pewan   +11 more
doaj   +2 more sources

A cytoskeletal vortex drives phage nucleus rotation during jumbo phage replication in E. coli. [PDF]

Cell Rep, 2022
AbstractVortex-like arrays of cytoskeletal filaments that drive cytoplasmic streaming and nucleus rotation have been identified in eukaryotes, but similar structures have not been described in prokaryotes. The only known example of a rotating intracellular body in prokaryotic cells occurs when nucleus-forming jumbo phages infect Pseudomonas.
Birkholz EA, Laughlin TG, Armbruster E, Suslov S, Lee J, Wittmann J, Corbett KD, Villa E, Pogliano J.   +8 more
europepmc   +5 more sources

Jumbo phage-mediated transduction of genomic islands. [PDF]

Proc Natl Acad Sci U S A
Bacteria acquire new genes by horizontal gene transfer (HGT), typically mediated by mobile genetic elements (MGEs). While plasmids, bacteriophages and certain integrative and conjugative elements (ICEs) are well characterized, the broader diversity of MGEs remains poorly understood. Here, we propagated the bacterium Pseudomonas fluorescens SBW25 in the
Zhao Y, Ma Y, Vasileiou C, Farr AD, Rogers DW, Rainey PB.   +5 more
europepmc   +5 more sources

Complete Genome Sequence of Klebsiella pneumoniae Jumbo Phage Miami. [PDF]

Microbiol Resour Announc, 2021
Bacteriophage Miami infects Klebsiella pneumoniae , a Gram-negative pathogen that is becoming an increasing threat to public health due to its multidrug resistance. Here, we describe the annotation of the 253,383-bp jumbo phage Miami genome sequence and its similarity to other myophages.
Mora D, Lessor L, Le T, Clark J, Gill JJ, Liu M.   +5 more
europepmc   +3 more sources

Unexplored diversity and molecular genetic signatures of chimallin and phuz encoding phages [PDF]

BMC Genomics
Nucleus-forming phages are a class of jumbo phages with the capacity to form a protein nuclear shell during infection within a bacterial host. This protein nuclear shell protects the replication of the phage genome by excluding host defense factors ...
Shize Sun, Cunyuan Li, Jia Sun, Xiaoyue Li, Min Liu, Xia Li, Kaiping Liu, Hui Li, Jinming Yu, Ping Zhou, Limin Wang, Kuojun Cai, Wei Ni, Shengwei Hu   +13 more
doaj   +2 more sources