Results 101 to 110 of about 112,531 (165)

p62/SQSTM1 Condensation Modulates Mitochondrial Clustering to Participate in Mitochondrial Quality Control

Aging Cell, Volume 25, Issue 2, February 2026.
In normal PINK1/Parkin‐mediated mitophagy, unlike OPTN (the mitophagy receptor that mediates ATG8‐labeled autophagosome recruitment onto ubiquitinated mitochondria), p62 mediates the clustering of ubiquitinated mitochondria to form the “grape‐like” aggregates with ubiquitin.
Shan Sun, Jiaqi Xin, Yingping Zhang, Bojun Yang, Dan Su, Rui Ni, Qilian Ma, Ningning Li, Guoqiang Ma, Qiang Peng, Siqian Chen, Jochen H. M. Prehn, Kin Yip Tam, Hongfeng Wang, Zheng Ying   +14 more
wiley   +1 more source

DNA Origami and Its Applications in Synthetic Biology

Advanced Science, Volume 13, Issue 2, 9 January 2026.
This review provides a comprehensive summary of recent advancements in DNA origami for synthetic biology, emphasizing two key areas: the precise construction and dynamic regulation of extracellular‐to‐intracellular, and the synergistic integration with cell‐free systems.
Yaning Fang, Xuexin Chen, Qingsheng Qi, Min Lin, Quanfeng Liang   +4 more
wiley   +1 more source

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, Volume 45, Issue 1, Page 69-106, January/February 2026.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source

Data_Sheet_1_vB_PaeM_MIJ3, a Novel Jumbo Phage Infecting Pseudomonas aeruginosa, Possesses Unusual Genomic Features.docx

, 2019
Phages are the most abundant biological entity on Earth. There are many variants in phage virion sizes, morphology, and genome sizes. Large virion sized phages, with genome sizes greater than 200 kbp have been identified and termed as Jumbo phages. These
Andrew Millard (761823), Ahmed S. A. Dowah (8054732), Edouard E. Galyov (7596533), Mohammed Imam (7768268), Nathan Brown (421008), Bandar Alrashid (8054726), Faizal Patel (8054729), Martha R. J. Clokie (6901562)   +7 more
core   +1 more source

Capsid Structure and DNA Packing in Jumbo Bacteriophages [PDF]

, 2016
Jumbo phages, the phages with genome length larger than 200 Kbp, are extreme examples of how the capsid and genome coordinate in evolution. To learn the mechanism of capsid size change during evolutionary time, the capsid and DNA of several jumbo phages ...
Hua, Jianfei
core  

Data_Sheet_1_Biological and Molecular Characterization of a Jumbo Bacteriophage Infecting Plant Pathogenic Ralstonia solanacearum Species Complex Strains.zip

, 2021
A jumbo phage infecting Ralstonia solanacearum species complex strains, designated RsoM2USA, was isolated from soil of a tomato field in Florida, United States, and belongs to the family Myoviridae.
Hardian Susilo Addy (6374231), Abdelmonim Ali Ahmad (4452463), Qi Huang (148030)   +2 more
core   +1 more source

Nucleus-Forming Jumbo Phage: Disrupting the Landscape of Phage Replication and Viral Speciation [PDF]

, 2022
This dissertation investigates the diversity and competition of nucleus-forming jumbo phage. The first chapter provides a brief history of the discovery of bacteriophages and their early use to combat bacterial infections, the detection of the first ...
Birkholz, Erica Ann
core  

New Genera and Species of Caulobacter and Brevundimonas Bacteriophages Provide Insights into Phage Genome Evolution

Viruses
Previous studies have identified diverse bacteriophages that infect Caulobacter vibrioides strain CB15 ranging from small RNA phages to four genera of jumbo phages.
Bert Ely, Michael Hils, Aaron Clarke, Maegan Albert, Nadia Holness, Jacob Lenski, Tannaz Mohammadi   +6 more
doaj   +1 more source

Jumbo Phage Bacterial Host genomes

The MAGs of two bacterial hosts of jumbo phages elucidated through CRISPR spacer matching. These were binned from metagenomic data using Metabat2.
Benjamin Minch (16495497)
core   +1 more source

Transcription Profiling of Bacillus subtilis Cells Infected with AR9, a Giant Phage Encoding Two Multisubunit RNA Polymerases

mBio, 2017
Bacteriophage AR9 is a recently sequenced jumbo phage that encodes two multisubunit RNA polymerases. Here we investigated the AR9 transcription strategy and the effect of AR9 infection on the transcription of its host, Bacillus subtilis.
Daria Lavysh, Maria Sokolova, Marina Slashcheva, Konrad U. Förstner, Konstantin Severinov   +4 more
doaj   +1 more source