Results 111 to 120 of about 112,531 (165)

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HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Jumbo Phages Assemble a Nucleus-Like Structure in Pseudomonas [PDF]

, 2019
Upon infection of host cells, jumbo Pseudomonas phages 201Φ2-1, ΦKZ, and ΦPA3 assemble a “phage nucleus” that encloses replicating viral DNA. The proteinaceous compartment segregates both phage and bacterial host proteins based on their function ...
Nguyen, Katrina
core  

Persistent virulent phages exist in bacterial isolates

bioRxiv
Despite the immense diversity of tailed bacteriophages, they are traditionally classified as either virulent or temperate, with only the latter thought capable of long-term persistence in bacterial cells through lysogeny.
Peter Erdmann Dougherty, Charles Bernard, A. B. Carstens, Kim Stanford, T. McAllister, Eduardo P. C. Rocha, L. H. Hansen   +6 more
semanticscholar   +1 more source

Identification of a large cohort of jumbo phages on an Enterobacter host that have broad host ranges across pathogenic Gammaproteobacteria.

ESKAPE pathogens cause the preponderance of hospital-acquired infections across the globe and have a high propensity for developing antibiotic resistance.
Kanhirun, Natasha
core  

High-throughput transposon mutagenesis defines the essential genome of diverse phages

bioRxiv
Phages are important drivers of bacterial evolution with therapeutic potential as antimicrobials. However, gaps in our understanding of phages and our inability to rapidly engineer them with new genetic cargo hinders progress towards phage-based ...
Natalie Kyte, Manuela Fuchs, Leah M. Smith, Peter C. Fineran   +3 more
semanticscholar   +1 more source

Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance

Frontiers in Microbiology
Phages, which play a crucial role in regulating bacterial populations and evolution, have gained renewed attention as potential therapeutic agents especially in the face of rising antimicrobial resistance, such as in Klebsiella pneumoniae– a MDR pathogen
Chandrasekar Karthika, Nambiraman Malligarjunan, Nagaiah Hari Prasath, Shunmugiah Karutha Pandian, Shanmugaraj Gowrishankar   +4 more
doaj   +1 more source

Genomic and phenotypic characterization of novel jumbo and small bacteriophages infecting Xanthomonas hortorum pv. vitians: Toward a phage-based biocontrol strategy

bioRxiv
In recent years, the use of bacteriophages as biocontrol agents has gained renewed attention, especially for targeting major phytopathogenic genera like Xanthomonas. However, their potential against Xanthomonas hortorum pv.
Anaelle Baud, Inès Rougis, Nicolas Taveau, Denis Costechareyre, Marie Graindorge Beaume, Franck Bertolla   +5 more
semanticscholar   +1 more source

Genome-wide identification of bacterial genes contributing to nucleus-forming jumbo phage infection

Nucleic Acids Research
The Chimalliviridae family of bacteriophages (phages) form a proteinaceous nucleus-like structure during infection of their bacterial hosts. This phage ‘nucleus’ compartmentalises phage DNA replication and transcription, and shields the phage genome from
Kate R. Harding, Lucia M. Malone, Natalie Kyte, Simon A. Jackson, Leah M. Smith, Peter C. Fineran   +5 more
semanticscholar   +1 more source

Architecture and self-assembly of the jumbo phage nucleus-like compartment

Biophysical Journal, 2022
Laughlin, Thomas G, Deep, Amar, Prichard, Amy M, Seitz, Christian, Gu, Yajie, Enustun, Eray, Suslov, Sergey, Khanna, Kanika, Birkholz, Erica A, Armbruster, Emily, Amaro, Rommie E, Pogliano, Joe, Corbett, Kevin D, Villa, Elizabeth   +13 more
openaire   +3 more sources

A Jumbo Phage Forms a Nucleus-like Compartment to Evade Bacterial Defense Systems [PDF]

Biochemistry, 2020
Ashley E. Modell, Sachini U. Siriwardena, Amit Choudhary   +2 more
openaire   +2 more sources