Characterization and Proteolytic Maturation of Head Proteins in a Giant Salmonella Virus [PDF]
, 2021 Giant phages are of interest for biocontrol of pathogenic bacteria, however, there is limited knowledge about their biology. We study the Salmonella phage SPN3US to better understand virion structure and function.
Scheuch, Aaron
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Exploring the transcriptional landscape of phagehost interactions using novel high-throughput approaches [PDF]
In the last decade, powerful high-throughput sequencing approaches have emerged to analyse microbial transcriptomes at a global scale. However, to date, applications of these approaches to microbial viruses such as phages remain scarce.
Azeredo, Joana +8 more
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An intron endonuclease facilitates interference competition between coinfecting viruses. [PDF]
Introns containing homing endonucleases are widespread in nature and have long been assumed to be selfish elements that provide no benefit to the host organism.
Armbruster, Emily +14 more
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Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance
Frontiers in MicrobiologyPhages, which play a crucial role in regulating bacterial populations and evolution, have gained renewed attention as potential therapeutic agents especially in the face of rising antimicrobial resistance, such as in Klebsiella pneumoniae– a MDR pathogen
Chandrasekar Karthika +4 more
doaj +1 more source
Coagulase-Negative Staphylococci phages panorama: genomic diversity and in vitro studies for a therapeutic use [PDF]
Coagulase-negative staphylococci (CoNS) are commensal bacteria of the human skin and mucosal membranes. The incidence of nosocomial infections caused by these species is on the rise, leading to a potential increase in antibiotic tolerance and resistance.
Azeredo, Joana +3 more
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Sequential membrane- and protein-bound organelles compartmentalize genomes during phage infection [PDF]
Many eukaryotic viruses require membrane-bound compartments for replication, but no such organelles are known to be formed by prokaryotic viruses. Bacteriophages of the Chimalliviridae family sequester their genomes within a phage-generated organelle ...
Adler, Benjamin A +26 more
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High niche specificity and host genetic diversity of groundwater viruses [PDF]
Viruses are key members of microbial communities that exert control over host abundance and metabolism, thereby influencing ecosystem processes and biogeochemical cycles.
Gios, Emilie +3 more
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PharmaceuticalsBackground: Combination therapy with antibiotics and phages has been suggested to increase the antibacterial activity of both antibiotics and phages. We tested the in vitro activity of five antibiotics belonging to different classes in combination with ...
Paschalis Paranos +3 more
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Tunturi virus isolates and metagenome-assembled viral genomes provide insights into the virome of Acidobacteriota in Arctic tundra soils [PDF]
BackgroundArctic soils are climate-critical areas, where microorganisms play crucial roles in nutrient cycling processes. Acidobacteriota are phylogenetically and physiologically diverse bacteria that are abundant and active in Arctic tundra soils. Still,
Demina, Tatiana +6 more
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A Jumbo Phage Forms a Nucleus-like Compartment to Evade Bacterial Defense Systems [PDF]
Biochemistry, 2020 Ashley E. Modell +2 more
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