Results 61 to 70 of about 9,671 (174)
Журнал микробиологии, эпидемиологии и иммунобиологии, 2015 Aim. Experience of study and possible ways of elimination of false positive and false negative results during execution of polymerase chain reaction on an example of Junin virus RNA detection. Materials and methods.
T. E Sizikova +4 more
doaj
Exploring the druggability of the UEV domain of human TSG101 in search for broad‐spectrum antivirals
Protein Science, Volume 34, Issue 1, January 2025.Abstract The ubiquitin E2 variant domain of TSG101 (TSG101‐UEV) plays a pivotal role in protein sorting and virus budding by recognizing PTAP motifs within ubiquitinated proteins. Disruption of TSG101‐UEV/PTAP interactions has emerged as a promising strategy for the development of host‐oriented broad‐spectrum antivirals with low susceptibility to ...
Fernando Montero +17 more
wiley +1 more source
Host Cell Factors as Antiviral Targets in Arenavirus Infection
Viruses, 2012 Among the members of the Arenaviridae family, Lassa virus and Junin virus generate periodic annual outbreaks of severe human hemorrhagic fever (HF) in endemic areas of West Africa and Argentina, respectively.
Elsa B. Damonte +6 more
doaj +1 more source
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus
Viruses, 2021 Arenaviruses cause chronic and asymptomatic infections in their natural host, rodents, and several arenaviruses cause severe hemorrhagic fever that has a high mortality in infected humans, seriously threatening public health.
Qingxing Wang +5 more
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Advances in Pharmacological and Pharmaceutical Sciences, Volume 2025, Issue 1, 2025.Due to its intricacy and long‐term usefulness, traditional medicine continues to be practiced in several nations. Among the many medicinal plants found in the Dhofar region of Oman, the aromatic oleo‐gum resin generated by Boswellia sacra, commonly referred to as frankincense, stands out for its medical and commercial significance. Resin‐carrying ducts
Foziya Khan, Luay Rashan, Kuldeep Singh
wiley +1 more source
Inter and intrapatient evolution of hepatitis C virus [PDF]
, 2015 Hepatitis C virus (HCV) has a short replication time, high mutation rates and large population sizes, all of which make it an excellent experimental model for evolution studies, because evolution can be visualized in real-time. In this review, we discuss
Campos, Rodolfo Hector +2 more
core +1 more source
National Seroprevalence and Risk Factors of Bluetongue Virus in Domestic Ruminants of Peru
Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.Bluetongue (BT) is a viral infection caused by the bluetongue virus (BTV) that affects domestic and wild ruminants worldwide. It is primarily transmitted by Culicoides spp. midges, and its infection is highly prevalent across temperate and tropical regions.
Dennis A. Navarro-Mamani +13 more
wiley +1 more source
Animal Models of Pathogenic New World Arenaviruses
MicroorganismsSince the emergence of Junín virus in 1953, pathogenic New World arenaviruses have remained a public health concern. These viruses, which also include Machupo virus, Guanarito virus, Sabiá virus, and Chapare virus, cause acute viral hemorrhagic fever and
Alexander V. Alvarado +3 more
doaj +1 more source
Tacaribe virus but not junin virus infection induces cytokine release from primary human monocytes and macrophages. [PDF]
PLoS Neglected Tropical Diseases, 2011 The mechanisms underlying the development of disease during arenavirus infection are poorly understood. However, common to all hemorrhagic fever diseases is the involvement of macrophages as primary target cells, suggesting that the immune response in ...
Allison Groseth +6 more
doaj +1 more source
Andean Lima Bean Ecology and Its Potential Contribution to Food Security
Legume Science, Volume 6, Issue 2, June 2024.ABSTRACT The Andean lima bean (ALB) (Phaseolus lunatus L.), also known as “Pallar” in Peru, is a large, semi‐flat, kidney‐shaped rarely investigated legume. This ancestral legume lacks in‐depth scientific reports and is mainly cultivated in the coastal region of the Ica valley. Its consumption dates back to ancient times, as evidenced by archaeological
Isabel Milagros Gavilan‐Figari +4 more
wiley +1 more source