Results 51 to 60 of about 2,613 (125)

Animal Models of Pathogenic New World Arenaviruses

open access: yesMicroorganisms
Since the emergence of Junín virus in 1953, pathogenic New World arenaviruses have remained a public health concern. These viruses, which also include Machupo virus, Guanarito virus, Sabiá virus, and Chapare virus, cause acute viral hemorrhagic fever and
Alexander V. Alvarado   +3 more
doaj   +1 more source

Analysis of the Cell Type-Dependence on the Arenavirus Z-Mediated Virus-Like Particle Production

open access: yesFrontiers in Microbiology, 2020
Several arenaviruses are highly pathogenic to humans, causing hemorrhagic fever. Discovery of anti-arenavirus drug candidates is urgently needed, although the molecular basis of the host- and organ-specific pathogenicity remains to be fully elucidated ...
Patrick I. Mpingabo   +6 more
doaj   +1 more source

Tacaribe virus but not junin virus infection induces cytokine release from primary human monocytes and macrophages. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2011
The mechanisms underlying the development of disease during arenavirus infection are poorly understood. However, common to all hemorrhagic fever diseases is the involvement of macrophages as primary target cells, suggesting that the immune response in ...
Allison Groseth   +6 more
doaj   +1 more source

Andean Lima Bean Ecology and Its Potential Contribution to Food Security

open access: yesLegume Science, Volume 6, Issue 2, June 2024.
ABSTRACT The Andean lima bean (ALB) (Phaseolus lunatus L.), also known as “Pallar” in Peru, is a large, semi‐flat, kidney‐shaped rarely investigated legume. This ancestral legume lacks in‐depth scientific reports and is mainly cultivated in the coastal region of the Ica valley. Its consumption dates back to ancient times, as evidenced by archaeological
Isabel Milagros Gavilan‐Figari   +4 more
wiley   +1 more source

Description and characterization of a novel live-attenuated tri-segmented Machupo virus in Guinea pigs

open access: yesVirology Journal, 2018
Background Machupo virus (MACV) is a member of the Mammarenavirus genus, Arenaviridae family and is the etiologic agent of Bolivian hemorrhagic fever, which causes small outbreaks or sporadic cases. Several other arenaviruses in South America Junín virus
Amélie D. Zaza   +2 more
doaj   +1 more source

Prevalence and Incidence of Parkinson's Disease in Latin America: A Meta‐Analysis

open access: yesMovement Disorders, Volume 39, Issue 1, Page 105-118, January 2024.
Abstract Background Parkinson's disease (PD) is a rapidly growing neurodegenerative disorder, but up‐to‐date epidemiological data are lacking in Latin America. We sought to estimate the prevalence and incidence of PD and parkinsonism in Latin America. Methods We searched Medline, Embase, Scopus, Web of Science, Scientific Electronic Library Online, and
Dani J. Kim   +9 more
wiley   +1 more source

Antimicrobial peptides for novel antiviral strategies in the current post‐COVID‐19 pandemic

open access: yesJournal of Peptide Science, Volume 30, Issue 1, January 2024.
This review describes the main physicochemical characteristics of antimicrobial peptides, with particular focus on peptides derived from amphibian skin. Summarizing the various antiviral activities of these peptides and the underlying mechanism, this review emphasizes the high potential of these small molecules for the development of new antiviral ...
Maria Rosa Loffredo   +3 more
wiley   +1 more source

Fiebres hemorrágicas por Arenavirus en Latinoamérica

open access: yesSalud Uninorte, 2010
Las fiebres hemorrágicas virales producidas por Arenavirus incluyen a los virus endémicos en África (Lassa) y el virus de la coriomeningitis linfocítica (LCMV), de distribución mundial, y los Arenavirus del Nuevo Mundo o Complejo Tacaribe, que incluye a ...
Ella Soto, Salim Mattar
doaj  

Virucidal Activity and Chemical Composition of Essential Oils from Aromatic Plants of Central West Argentina

open access: yesNatural Product Communications, 2010
The essential oils of seven aromatic plants from central west argentina were isolated by steam distillation and analyzed by a gas chromatography mass spectrometry technique. The oils were screened for cytotoxicity and In Vitro inhibitory activity against
Cybele C. García   +8 more
doaj   +1 more source

Multi-epitope-based vaccine designing against Junín virus glycoprotein: immunoinformatics approach

open access: yesFuture Journal of Pharmaceutical Sciences
Background The Junín virus (JUNV) is well known for causing argentine haemorrhagic fever (AHF), a severe endemic disease in farming premises. The glycoprotein of JUNV is an important therapeutic target in vaccine design.
Mallari Praveen
doaj   +1 more source

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